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Binding of SLBP to Replication-Dependent Histone Pre-mRNA
Stable Identifier
R-HSA-77584
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism of RNA (Homo sapiens)
Processing of Capped Intronless Pre-mRNA (Homo sapiens)
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs (Homo sapiens)
Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The 32 kDa stem-loop binding protein (SLBP), also termed hairpin binding protein (HBP) is likely the first protein that binds to the histone pre-mRNA as it is being transcribed.
Literature References
PubMed ID
Title
Journal
Year
9049306
The gene for histone RNA hairpin binding protein is located on human chromosome 4 and encodes a novel type of RNA binding protein.
Schumperli, D
,
Müller, B
,
Eglite, S
,
Martin, F
,
Schaller, A
EMBO J
1997
Participants
Input
Capped Intronless Histone pre-mRNA:CBC complex [nucleoplasm]
(Homo sapiens)
SLBP [nucleoplasm]
(Homo sapiens)
Output
Capped Intronless Histone pre-mRNA:CBP80:CBP20:SLBP [nucleoplasm]
(Homo sapiens)
Participates
as an event of
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs (Homo sapiens)
Event Information
Go Biological Process
mRNA 3'-end processing by stem-loop binding and cleavage (0006398)
Orthologous Events
Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Bos taurus)
Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Caenorhabditis elegans)
Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Canis familiaris)
Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Dictyostelium discoideum)
Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Drosophila melanogaster)
Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Gallus gallus)
Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Mus musculus)
Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Rattus norvegicus)
Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Sus scrofa)
Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Xenopus tropicalis)
Authored
Marzluff, WF (2003-08-22)
Created
Marzluff, WF (2003-08-22)
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