3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA

Stable Identifier
R-HSA-77340
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
3-oxodecanoyl-CoA + CoA => octanoyl-CoA + acetyl-CoA
ReviewStatus
5/5
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3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Trifunctional protein in the mitochondrial matrix converts 3-oxodecanoyl-CoA to octanoyl-CoA plus acetyl-CoA (Carpenter et al. 1992).
Literature References
PubMed ID Title Journal Year
1550553 Human liver long-chain 3-hydroxyacyl-coenzyme A dehydrogenase is a multifunctional membrane-bound beta-oxidation enzyme of mitochondria.

Carpenter, K, Pollitt, RJ, Middleton, B

Biochem Biophys Res Commun 1992
Participants
Input
Output
Participates
as an event of
Catalyst Activity

acetyl-CoA C-acyltransferase activity of Trifunctional Protein [mitochondrial matrix]

Physical Entity
Trifunctional Protein [mitochondrial matrix] (Homo sapiens)
Activity
acetyl-CoA C-acyltransferase activity (GO:0003988)
Orthologous Events
3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA (Bos taurus)
3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA (Caenorhabditis elegans)
3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA (Canis familiaris)
3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA (Danio rerio)
3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA (Drosophila melanogaster)
3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA (Gallus gallus)
3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA (Mus musculus)
3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA (Rattus norvegicus)
3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA (Sus scrofa)
3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA (Xenopus tropicalis)
Cross References
RHEA
Created
Gillespie, ME  (2003-09-19)
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