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PLPP2 [plasma membrane]
Stable Identifier
R-HSA-76128
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
PPAP2C, Phosphatidate phosphatase (PPAP2C), LPP2
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Sphingolipid metabolism (Homo sapiens)
Sphingolipid catabolism (Homo sapiens)
PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate (Homo sapiens)
PLPP1,2,3 [plasma membrane] (Homo sapiens)
PLPP2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43688 PLPP2
Gene Names
PLPP2, LPP2, PPAP2C
Chain
chain:1-288
Reference Genes
BioGPS Gene:8612 PLPP2
COSMIC (genes):PLPP2 PLPP2
CTD Gene:8612 PLPP2
dbSNP Gene:8612 PLPP2
ENSEMBL:ENSG00000141934 PLPP2
ENSEMBL_homo_sapiens_GENE:ENSG00000141934.10 PLPP2
HGNC:9230 PLPP2
KEGG Gene (Homo sapiens):8612 PLPP2
Monarch:8612 PLPP2
NCBI Gene:8612 PLPP2
OMIM:607126 PLPP2
UCSC:O43688 PLPP2
Reference Transcript
RefSeq:NM_177526.2 PLPP2
RefSeq:NM_177543.2 PLPP2
RefSeq:NM_003712.3 PLPP2
Other Identifiers
11720294_a_at
11734720_a_at
16866394
209529_PM_at
209529_at
34771_at
3844471
3844472
3844474
3844475
3844477
3844478
3844479
3844482
3844483
3844484
3844485
8031999
8612
A_23_P108294
GE54290
GO:0003824
GO:0005515
GO:0005768
GO:0005769
GO:0005783
GO:0005789
GO:0005886
GO:0005901
GO:0006629
GO:0006644
GO:0006665
GO:0006670
GO:0006672
GO:0007165
GO:0008195
GO:0016020
GO:0016787
GO:0023052
GO:0031410
GO:0031901
GO:0042392
GO:0043226
GO:0046839
GO:0106235
HMNXSV003044649
ILMN_1675523
ILMN_1710170
ILMN_2405156
PH_hs_0002182
TC19000981.hg
g2911497_3p_at
Participates
as a member of
PLPP1,2,3 [plasma membrane] (Homo sapiens)
Inferred To
wun [plasma membrane]
(Drosophila melanogaster)
plpp-1.2 [plasma membrane]
(Caenorhabditis elegans)
Plpp2 [plasma membrane]
(Mus musculus)
Plpp2 [plasma membrane]
(Rattus norvegicus)
DPP1 [plasma membrane]
(Saccharomyces cerevisiae)
plpp2 [plasma membrane]
(Xenopus tropicalis)
LPP1 [plasma membrane]
(Saccharomyces cerevisiae)
WUN-like [plasma membrane]
(Drosophila melanogaster)
PLPP2 [plasma membrane]
(Bos taurus)
PLPP2 [plasma membrane]
(Canis familiaris)
PLPP2 [plasma membrane]
(Dictyostelium discoideum)
PLPP2 [plasma membrane]
(Gallus gallus)
PLPP2 [plasma membrane]
(Sus scrofa)
dpp1 [plasma membrane]
(Schizosaccharomyces pombe)
plpp-1.1 [plasma membrane]
(Caenorhabditis elegans)
plpp-1.3 [plasma membrane]
(Caenorhabditis elegans)
LPP-like [plasma membrane]
(Drosophila melanogaster)
wun2 [plasma membrane]
(Drosophila melanogaster)
Homologues of PLPP2 [plasma membrane]
(Caenorhabditis elegans)
Homologues of PLPP2 [plasma membrane]
(Dictyostelium discoideum)
Homologues of PLPP2 [plasma membrane]
(Drosophila melanogaster)
Homologues of PLPP2 [plasma membrane]
(Saccharomyces cerevisiae)
laza [plasma membrane]
(Drosophila melanogaster)
plpp2b [plasma membrane]
(Danio rerio)
Cross References
RefSeq
NP_808211.1
,
NP_003703.1
,
NP_803545.1
Guide to Pharmacology - Targets
1440
OpenTargets
ENSG00000141934
IntEnz
3.1.3.4
HPA
ENSG00000141934-PLPP2
GeneCards
O43688
Ensembl
ENSG00000141934
,
ENST00000269812
,
ENSP00000329697
,
ENSP00000269812
,
ENST00000434325
,
ENSP00000388565
,
ENST00000327790
PRO
O43688
Pharos - Targets
O43688
HMDB Protein
HMDBP00231
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