Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP

Stable Identifier
R-HSA-75866
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
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At the beginning of this reaction, 1 molecule of 'Pol II initiation complex' is present. At the end of this reaction, 1 molecule of 'Pol II Initiation complex with phosphodiester-PPi intermediate' is present.

This reaction takes place in the 'nucleus'.

Literature References
PubMed ID Title Journal Year
9405375 Three transitions in the RNA polymerase II transcription complex during initiation.

Holstege, FC, Fiedler, U, Timmers, HT

EMBO J 1998
Participants
Participant Of
Orthologous Events
Created
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