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SLC35D2 [Golgi membrane]
Stable Identifier
R-HSA-744235
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter, S35D2_HUMAN, UDP-galactose transporter-related protein 8, UGTREL8, Homolog of Fringe connection protein 1, HFRC
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Glucuronidation (Homo sapiens)
Formation of the active cofactor, UDP-glucuronate (Homo sapiens)
SLC35D2 exchanges UDP-GlcA for UMP (Homo sapiens)
SLC35D2 [Golgi membrane] (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Heparan sulfate/heparin (HS-GAG) metabolism (Homo sapiens)
HS-GAG biosynthesis (Homo sapiens)
SLC35D2 exchanges UDP-GlcNAc for UMP (Homo sapiens)
SLC35D2 [Golgi membrane] (Homo sapiens)
Keratan sulfate/keratin metabolism (Homo sapiens)
Keratan sulfate biosynthesis (Homo sapiens)
SLC35D2 exchanges UDP-GlcNAc for UMP (Homo sapiens)
SLC35D2 [Golgi membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of nucleotide sugars (Homo sapiens)
SLC35D2 exchanges UDP-D-glucose for UMP (Homo sapiens)
SLC35D2 [Golgi membrane] (Homo sapiens)
SLC35D2 exchanges UDP-GlcA for UMP (Homo sapiens)
SLC35D2 [Golgi membrane] (Homo sapiens)
SLC35D2 exchanges UDP-GlcNAc for UMP (Homo sapiens)
SLC35D2 [Golgi membrane] (Homo sapiens)
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP (Homo sapiens)
SLC35D2 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q76EJ3 SLC35D2
Gene Names
SLC35D2, HFRC, UGTREL8
Chain
chain:1-337
Reference Genes
BioGPS Gene:11046 SLC35D2
COSMIC (genes):SLC35D2 SLC35D2
CTD Gene:11046 SLC35D2
dbSNP Gene:11046 SLC35D2
ENSEMBL:ENSG00000130958 SLC35D2
HGNC:20799 SLC35D2
KEGG:hsa:11046 SLC35D2
Monarch:11046 SLC35D2
NCBI Gene:11046 SLC35D2
OMIM:609182 SLC35D2
UCSC:Q76EJ3 SLC35D2
Reference Transcript
RefSeq:NM_001286990.1 SLC35D2
RefSeq:NM_007001.2 SLC35D2
Other Identifiers
11046
11718931_a_at
17096188
213082_PM_s_at
213082_s_at
213083_PM_at
213083_at
231437_PM_at
231437_at
233325_PM_at
233325_at
3216277
3216279
3216280
3216281
3216284
3216285
3216287
3216290
3216291
3216292
3216297
3216298
3216300
3216303
3216305
3216310
3216312
3216313
3216317
3216318
38005_at
44337_f_at
55354_f_at
63515_at
74925_at
8162586
A_23_P32029
A_33_P3278187
GE778602
GE80188
GO:0000139
GO:0005215
GO:0005338
GO:0005461
GO:0005462
GO:0005463
GO:0005794
GO:0006790
GO:0008150
GO:0015012
GO:0015297
GO:0015780
GO:0015787
GO:0015789
GO:0016020
GO:0018146
GO:0043226
GO:0055085
GO:1901135
GO:1990569
HMNXSV003018381
HMNXSV003031705
Hs.325305.0.S1_3p_at
Hs.90078.0.S1_3p_at
Hs.90078.1.A1_3p_at
ILMN_1706571
PH_hs_0024386
PH_hs_0026993
PH_hs_0035883
TC09001374.hg
Inferred To
SLC35D2 [Golgi membrane]
(Bos taurus)
SLC35D2 [Golgi membrane]
(Dictyostelium discoideum)
SLC35D2 [Golgi membrane]
(Gallus gallus)
SLC35D2 [Golgi membrane]
(Sus scrofa)
sqv-7 [Golgi membrane]
(Caenorhabditis elegans)
frc [Golgi membrane]
(Drosophila melanogaster)
Slc35d2 [Golgi membrane]
(Mus musculus)
Slc35d2 [Golgi membrane]
(Rattus norvegicus)
HSD17B3 [Golgi membrane]
(Canis familiaris)
slc35d2 [Golgi membrane]
(Xenopus tropicalis)
Cross References
Guide to Pharmacology - Targets
1150
ENSEMBL
ENSP00000364408
,
ENST00000253270
,
ENST00000375259
,
ENSP00000253270
OpenTargets
ENSG00000130958
HPA
ENSG00000130958-SLC35D2
PRO
Q76EJ3
Pharos - Targets
Q76EJ3
HMDB Protein
HMDBP11933
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