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RRN3 [nucleoplasm]
Stable Identifier
R-HSA-73714
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Rrn3
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase I Transcription (Homo sapiens)
RNA Polymerase I Promoter Clearance (Homo sapiens)
RNA Polymerase I Promoter Escape (Homo sapiens)
Loss of Rrn3 from RNA Polymerase I promoter escape complex (Homo sapiens)
RNA Polymerase I Transcription Initiation complex [nucleoplasm] (Homo sapiens)
Active RNA Polymerase I [nucleoplasm] (Homo sapiens)
RRN3 [nucleoplasm] (Homo sapiens)
RRN3 [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Initiation (Homo sapiens)
Binding of RRN3 to RNA Polymerase I (Homo sapiens)
Active RNA Polymerase I [nucleoplasm] (Homo sapiens)
RRN3 [nucleoplasm] (Homo sapiens)
RRN3 [nucleoplasm] (Homo sapiens)
Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Homo sapiens)
Active RNA Polymerase I [nucleoplasm] (Homo sapiens)
RRN3 [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Initiation complex [nucleoplasm] (Homo sapiens)
Active RNA Polymerase I [nucleoplasm] (Homo sapiens)
RRN3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NYV6 RRN3
Gene Names
RRN3, TIFIA
Chain
chain:1-651
Reference Genes
BioGPS Gene:54700 RRN3
COSMIC (genes):RRN3 RRN3
CTD Gene:54700 RRN3
dbSNP Gene:54700 RRN3
ENSEMBL:ENSG00000085721 RRN3
HGNC:30346 RRN3
Monarch:54700 RRN3
NCBI Gene:54700 RRN3
OMIM:605121 RRN3
UCSC:Q9NYV6 RRN3
Reference Transcript
RefSeq:NM_018427.4 RRN3
Other Identifiers
11719605_at
11719606_a_at
11719607_x_at
11746373_s_at
16824143
216902_PM_s_at
216902_s_at
216908_PM_x_at
216908_x_at
222204_PM_s_at
222204_s_at
34967_at
3652219
3655215
3655216
3655217
3655219
3655220
3655222
3655223
3655224
3655225
3655226
3655227
3655228
3655231
3655233
3655234
3655236
3655237
3681706
3681707
3681708
3681709
3681710
3681711
3681712
3681713
3681714
3681715
3681716
3681717
3681718
3681719
3681721
3681722
3681723
3681724
3681726
3681727
3681728
3681729
3681731
3681732
3681736
3684558
3684559
3684560
3684561
3684563
3684564
3684565
3684566
3684570
3684573
3684575
3684576
3684577
3684580
3684582
3684588
3684595
3684819
3684820
3684821
3684822
3684823
54700
65518_at
74687_at
7994565
7999608
8000192
8000200
A_23_P206877
A_24_P382017
GE54040
GO:0001042
GO:0001164
GO:0001181
GO:0001188
GO:0001701
GO:0003677
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0006352
GO:0006355
GO:0006361
GO:0007000
GO:0007028
GO:0042254
GO:0043226
GO:0045893
GO:0048144
GO:0048856
GO:0048872
GO:0065003
GO:0070063
GO:0072332
GO:0140223
GO:1902254
GO:2000142
HMNXSV003000776
HMNXSV003047133
Hs.110103.2.A1_3p_s_at
Hs.110103.3.A1_3p_a_at
Hs.189834.0.S1_3p_s_at
ILMN_1765401
PH_hs_0006073
TC16000316.hg
TC16000892.hg
TC16001474.hg
TC16001806.hg
Participates
as an input of
Binding of RRN3 to RNA Polymerase I (Homo sapiens)
as an output of
Loss of Rrn3 from RNA Polymerase I promoter escape complex (Homo sapiens)
as a component of
Active RNA Polymerase I [nucleoplasm] (Homo sapiens)
Inferred To
Rrn3 [nucleoplasm]
(Mus musculus)
Rrn3 [nucleoplasm]
(Rattus norvegicus)
RRN3 [nucleoplasm]
(Bos taurus)
RRN3 [nucleoplasm]
(Caenorhabditis elegans)
RRN3 [nucleoplasm]
(Canis familiaris)
RRN3 [nucleoplasm]
(Dictyostelium discoideum)
RRN3 [nucleoplasm]
(Gallus gallus)
RRN3 [nucleoplasm]
(Saccharomyces cerevisiae)
RRN3 [nucleoplasm]
(Sus scrofa)
Tif-IA [nucleoplasm]
(Drosophila melanogaster)
rrn3 [nucleoplasm]
(Schizosaccharomyces pombe)
rrn3 [nucleoplasm]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENST00000327307
,
ENST00000198767
,
ENST00000616334
,
ENSP00000198767
,
ENSP00000480743
,
ENST00000632541
,
ENSP00000454238
,
ENSP00000487821
,
ENSP00000488651
,
ENST00000564131
,
ENST00000634151
,
ENSP00000318484
OpenTargets
ENSG00000085721
HPA
ENSG00000085721-RRN3
PRO
Q9NYV6
Pharos - Targets
Q9NYV6
PDB
7OBA
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6UXF1 TM108
0.527
2
UniProt:O95602 POLR1A
1
POLR1A [nucleoplasm]
(R-HSA-63494)
0.527
3
UniProt:Q9GZS1 POLR1E
1
POLR1E [nucleoplasm]
(R-HSA-5419294)
0.527
3
UniProt:Q3B726 POLR1F
1
TWISTNB [nucleoplasm]
(R-HSA-5419290)
0.527
3
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