Reactome | TYMP [cytosol]

TYMP [cytosol]

Stable Identifier

R-HSA-73610

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

thymidine phosphorylase, endothelial cell growth factor 1 (platelet-derived), Thymidine phosphorylase precursor (EC 2.4.2.4) (TdRPase) (TP) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (Gliostatin), Thymidine phosphorylase precursor , TdRPase, TP, Platelet-derived endothelial cell growth factor, PD-ECGF, Gliostatin

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P19971 TYMP

Gene Names

TYMP, ECGF1

Chain

propeptide:1-10, chain:11-482

Reference Genes

BioGPS Gene:1890 TYMP

COSMIC (genes):TYMP TYMP

CTD Gene:1890 TYMP

dbSNP Gene:1890 TYMP

ENSEMBL:ENSG00000025708 TYMP

HGNC:3148 TYMP

KEGG Gene (Homo sapiens):1890 TYMP

Monarch:1890 TYMP

NCBI Gene:1890 TYMP

OMIM:131222 TYMP

UCSC:P19971 TYMP

Reference Transcript

Other Identifiers

0005860066

11722449_x_at

1665_s_at

1890

204858_3p_s_at

204858_s_at

36879_at

3966001

3966002

3966003

3966004

3966005

3966009

3966011

3966013

3966014

3966017

3966018

3966019

8077103

A_23_P91802

A_24_P402261

A_33_P3255949

GE79180

GO:0000002

GO:0001525

GO:0003674

GO:0004645

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005829

GO:0006206

GO:0006213

GO:0006935

GO:0007005

GO:0007165

GO:0007275

GO:0008083

GO:0008150

GO:0009032

GO:0009056

GO:0009058

GO:0016154

GO:0016740

GO:0016757

GO:0016763

GO:0030154

GO:0031641

GO:0034641

GO:0034655

GO:0040011

GO:0042803

GO:0043097

GO:0044281

GO:0046135

GO:0048646

GO:0048856

GO:0050877

GO:0051969

GO:1905333

ILMN_1690939

ILMN_1738867

ILMN_2109708

ILMN_3223126

ILMN_3297126

PH_hs_0025381

S72487_at

TC22001418.hg

TC22001500.hg

g7669488_3p_a_at

Participant Of

hasComponent

TYMP dimer [cytosol]

Inferred To

Tymp [cytosol] (Mus musculus)

Tymp [cytosol] (Rattus norvegicus)

tymp [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001244918.1, NP_001107228.1, NP_001244917.1, NP_001944.1, NP_001107227.1

ZINC - World Drugs

TYPH_HUMAN

OpenTargets

ENSG00000025708

ZINC - FDA approved

TYPH_HUMAN

ZINC - Substances

TYPH_HUMAN

ZINC target

P19971

PRO

P19971

PDB

2J0F, 2WK6, 1UOU, 2WK5

IntEnz

2.4.2.4

HPA

ENSG00000025708-TYMP

GeneCards

P19971

Ensembl

ENSP00000379036, ENST00000395678, ENSP00000379037, ENSP00000498844, ENSP00000252029, ENST00000252029, ENST00000487577, ENSG00000025708, ENSP00000379038, ENST00000395680, ENST00000395681

Orphanet

17356

ZINC - Predictions - Purchasable

TYPH_HUMAN

HMDB Protein

HMDBP03818