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TYMP [cytosol]
Stable Identifier
R-HSA-73610
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
thymidine phosphorylase, endothelial cell growth factor 1 (platelet-derived), Thymidine phosphorylase precursor (EC 2.4.2.4) (TdRPase) (TP) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (Gliostatin), Thymidine phosphorylase precursor , TdRPase, TP, Platelet-derived endothelial cell growth factor, PD-ECGF, Gliostatin
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Nucleotide catabolism (Homo sapiens)
Pyrimidine catabolism (Homo sapiens)
thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] (Homo sapiens)
TYMP dimer [cytosol] (Homo sapiens)
TYMP [cytosol] (Homo sapiens)
Nucleotide salvage (Homo sapiens)
Pyrimidine salvage (Homo sapiens)
thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] (Homo sapiens)
TYMP dimer [cytosol] (Homo sapiens)
TYMP [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P19971 TYMP
Gene Names
TYMP, ECGF1
Chain
propeptide:1-10, chain:11-482
Reference Genes
BioGPS Gene:1890 TYMP
COSMIC (genes):TYMP TYMP
CTD Gene:1890 TYMP
dbSNP Gene:1890 TYMP
ENSEMBL:ENSG00000025708 TYMP
HGNC:3148 TYMP
KEGG:hsa:1890 TYMP
Monarch:1890 TYMP
NCBI Gene:1890 TYMP
OMIM:131222 TYMP
UCSC:P19971 TYMP
Reference Transcript
RefSeq:NM_001113755.2 TYMP
RefSeq:NM_001257988.1 TYMP
RefSeq:NM_001257989.1 TYMP
RefSeq:NM_001953.4 TYMP
RefSeq:NM_001113756.2 TYMP
Other Identifiers
11722449_x_at
11760977_a_at
11761147_at
1665_s_at
1890
204858_3p_s_at
204858_PM_s_at
204858_s_at
217497_3p_at
217497_PM_at
217497_at
36879_at
3965991
3965993
3965995
3965997
3965999
3966001
3966002
3966003
3966004
3966005
3966006
3966007
3966008
3966009
3966010
3966011
3966012
3966013
3966014
3966015
3966016
3966017
3966018
3966019
3966037
8077103
A_23_P91802
A_24_P402261
A_33_P3255949
GE79180
GE87327
GO:0000002
GO:0001525
GO:0003824
GO:0004645
GO:0005515
GO:0005829
GO:0006206
GO:0006213
GO:0006935
GO:0007005
GO:0007165
GO:0008083
GO:0009032
GO:0016154
GO:0016740
GO:0016757
GO:0016763
GO:0030154
GO:0031641
GO:0042803
GO:0046074
GO:0048018
GO:0051969
GO:0055086
GO:0098772
GO:1901135
GO:1905333
Hs.278541.0.S1_3p_at
Hs.278541.0.S1_3p_x_at
ILMN_1690939
ILMN_1738867
ILMN_2109708
PH_hs_0025381
PH_hs_0038858
PH_hs_0039518
S72487_at
TC22001418.hg
TC22001500.hg
g7669488_3p_a_at
Participates
as a component of
TYMP dimer [cytosol] (Homo sapiens)
Inferred To
Tymp [cytosol]
(Rattus norvegicus)
TYMP [cytosol]
(Mus musculus)
tymp [cytosol]
(Xenopus tropicalis)
Cross References
ZINC - World Drugs
TYPH_HUMAN
ENSEMBL
ENST00000395681
,
ENST00000395680
,
ENSP00000252029
,
ENSP00000379038
,
ENST00000487577
,
ENST00000252029
,
ENSP00000379036
,
ENSP00000379037
,
ENST00000395678
,
ENSP00000498844
OpenTargets
ENSG00000025708
ZINC - FDA approved
TYPH_HUMAN
ZINC - Substances
TYPH_HUMAN
ZINC target
P19971
PRO
P19971
GlyGen
P19971
PDB
2J0F
,
2WK6
,
2WK5
,
1UOU
HPA
ENSG00000025708-TYMP
Pharos - Targets
P19971
Orphanet
TYMP
ZINC - Predictions - Purchasable
TYPH_HUMAN
HMDB Protein
HMDBP03818
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BW85 YJU2
1
YJU2 [nucleoplasm]
(R-HSA-9770430)
0.527
2
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