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SDHC [mitochondrial inner membrane]
Stable Identifier
R-HSA-70988
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
Succinate Dehydrogenase complex subunit C, Succinate dehydrogenase cytochrome b560 subunit, mitochondrial precursor, Integral membrane protein CII-3, QPS1, QPs-1, Succinate dehydrogenase complex subunit C, Succinate-ubiquinone oxidoreductase cytochrome B large subunit, CYBL
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
Maturation of TCA enzymes and regulation of TCA cycle (Homo sapiens)
SDHA:SDHB binds to SDHC:SDHD (Homo sapiens)
SDH complex [mitochondrial inner membrane] (Homo sapiens)
SDHC:SDHD:heme b [mitochondrial inner membrane] (Homo sapiens)
SDHC [mitochondrial inner membrane] (Homo sapiens)
SDHC:SDHD:heme b [mitochondrial inner membrane] (Homo sapiens)
SDHC [mitochondrial inner membrane] (Homo sapiens)
SDH complex dehydrogenates succinate (Homo sapiens)
SDH complex [mitochondrial inner membrane] (Homo sapiens)
SDHC:SDHD:heme b [mitochondrial inner membrane] (Homo sapiens)
SDHC [mitochondrial inner membrane] (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Transfer of electrons through the succinate dehydrogenase complex (Homo sapiens)
SDH complex [mitochondrial inner membrane] (Homo sapiens)
SDHC:SDHD:heme b [mitochondrial inner membrane] (Homo sapiens)
SDHC [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99643 SDHC
Gene Names
SDHC, CYB560, SDH3
Chain
transit peptide:1-29, chain:30-169
Reference Genes
BioGPS Gene:6391 SDHC
COSMIC (genes):SDHC SDHC
CTD Gene:6391 SDHC
dbSNP Gene:6391 SDHC
ENSEMBL:ENSG00000143252 SDHC
ENSEMBL_homo_sapiens_GENE:ENSG00000143252.16 SDHC
HGNC:10682 SDHC
KEGG Gene (Homo sapiens):6391 SDHC
Monarch:6391 SDHC
NCBI Gene:6391 SDHC
OMIM:602413 SDHC
UCSC:Q99643 SDHC
Reference Transcript
RefSeq:NM_001035511.1 SDHC
RefSeq:NM_001278172.1 SDHC
RefSeq:NM_003001.3 SDHC
RefSeq:NM_001035512.1 SDHC
RefSeq:NM_001035513.1 SDHC
Other Identifiers
11715840_s_at
11736758_x_at
11736759_s_at
11751869_s_at
16672872
202004_PM_x_at
202004_x_at
210131_PM_x_at
210131_x_at
215088_PM_s_at
215088_s_at
216591_3p_s_at
216591_PM_s_at
216591_s_at
2363619
2363624
2363628
2363632
2363636
2363637
2363638
2363639
3364966
34385_at
3740739
3740741
3740743
6391
7906746
8011212
A_24_P233850
A_33_P3410724
GE59255
GO:0000104
GO:0003824
GO:0005515
GO:0005739
GO:0005743
GO:0005749
GO:0006091
GO:0006099
GO:0006121
GO:0009055
GO:0009060
GO:0016020
GO:0016491
GO:0016627
GO:0020037
GO:0022900
GO:0042776
GO:0043226
GO:0045257
GO:0045281
GO:0046872
GO:0055086
GO:1901135
HMNXSV003044694
Hs.247725.0.S1_3p_s_at
TC01001385.hg
U57877_at
g2588778_3p_a_at
Participates
as a component of
SDHC:SDHD:heme b [mitochondrial inner membrane] (Homo sapiens)
Inferred To
Succinate dehydrogenase QPS1 [mitochondrial inner membrane]
(Bos taurus)
Ghost homologue of SDHC [mitochondrial inner membrane]
(Caenorhabditis elegans)
SDHC [mitochondrial inner membrane]
(Bos taurus)
SDHC [mitochondrial inner membrane]
(Canis familiaris)
SDHC [mitochondrial inner membrane]
(Dictyostelium discoideum)
SDHC [mitochondrial inner membrane]
(Gallus gallus)
SDHC [mitochondrial inner membrane]
(Mus musculus)
SDHC [mitochondrial inner membrane]
(Saccharomyces cerevisiae)
SDHC [mitochondrial inner membrane]
(Schizosaccharomyces pombe)
SDHC [mitochondrial inner membrane]
(Sus scrofa)
SdhC [mitochondrial inner membrane]
(Drosophila melanogaster)
sdhc [mitochondrial inner membrane]
(Danio rerio)
sdhc [mitochondrial inner membrane]
(Xenopus tropicalis)
Homologues of SDHC [mitochondrial inner membrane]
(Bos taurus)
Sdhc [mitochondrial inner membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_001265101.1
,
NP_001030590.1
,
NP_001030589.1
,
NP_001030588.1
,
NP_002992.1
OpenTargets
ENSG00000143252
GeneCards
Q99643
HPA
ENSG00000143252-SDHC
Ensembl
ENSG00000143252
,
ENST00000513009
,
ENSP00000376009
,
ENST00000432287
,
ENSP00000423260
,
ENSP00000390558
,
ENST00000342751
,
ENSP00000356953
,
ENST00000392169
,
ENST00000367975
,
ENSP00000356952
PRO
Q99643
Pharos - Targets
Q99643
Orphanet
15263
PDB
8GS8
HMDB Protein
HMDBP00121
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q92993 KAT5
1
KAT5 [nucleoplasm]
(R-HSA-3321979)
0.556
3
UniProt:P17252 PRKCA
8
PRKCA [nucleoplasm]
(R-HSA-450530)
PRKCA [photoreceptor disc membrane]
(R-HSA-2648987)
PRKCA [cytosol]
(R-HSA-58196)
pT497,T638,S657-PRKCA [plasma membrane]
(R-HSA-4332340)
p-T497-PRKCA [cytosol]
(R-HSA-5218731)
p-T497,T638,S657-PRKCA [cytosol]
(R-HSA-4332337)
p-T497,T638,S657-PRKCA [nucleoplasm]
(R-HSA-5223292)
PRKCA [plasma membrane]
(R-HSA-156469)
0.556
3
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