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IDH3G [mitochondrial matrix]
Stable Identifier
R-HSA-70964
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
isocitrate dehydrogenase 3 (NAD+) gamma, Isocitrate dehydrogenase (NAD) subunit gamma, mitochondrial precursor, Isocitric dehydrogenase, NAD+-specific ICDH
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
IDH3 complex decarboxylates isocitrate (Homo sapiens)
IDH3 octamer [mitochondrial matrix] (Homo sapiens)
IDH3 complex [mitochondrial matrix] (Homo sapiens)
IDH3G [mitochondrial matrix] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
20435888
Each conserved active site tyr in the three subunits of human isocitrate dehydrogenase has a different function
Dange, M
,
Colman, RF
J Biol Chem
2010
External Reference Information
External Reference
UniProt:P51553 IDH3G
Gene Names
IDH3G
Chain
transit peptide:1-39, chain:40-393
Reference Genes
BioGPS Gene:3421 IDH3G
COSMIC (genes):IDH3G IDH3G
CTD Gene:3421 IDH3G
dbSNP Gene:3421 IDH3G
ENSEMBL:ENSG00000067829 IDH3G
HGNC:5386 IDH3G
KEGG:hsa:3421 IDH3G
Monarch:3421 IDH3G
NCBI Gene:3421 IDH3G
OMIM:300089 IDH3G
UCSC:P51553 IDH3G
Reference Transcript
RefSeq:NM_004135.4 IDH3G
RefSeq:NM_174869.3 IDH3G
Other Identifiers
11726266_a_at
17115229
202471_PM_s_at
202471_s_at
214333_3p_x_at
214333_PM_x_at
214333_x_at
3421
36574_at
4026723
4026724
4026725
4026726
4026727
4026728
4026729
4026730
4026731
4026732
4026733
4026734
4026735
4026736
4026737
4026739
4026740
4026741
4026742
4026746
4026747
4026748
4026750
4026753
4026754
8175844
A_23_P34115
GE59134
GO:0000287
GO:0003824
GO:0004449
GO:0005515
GO:0005524
GO:0005730
GO:0005739
GO:0005759
GO:0005975
GO:0006099
GO:0006102
GO:0016491
GO:0016616
GO:0043226
GO:0045242
GO:0046872
GO:0051287
Hs.75253.1.A1_3p_a_at
Hs.75253.1.A1_3p_at
Hs.75253.1.A1_3p_x_at
ILMN_1682762
ILMN_1802706
PH_hs_0024824
TC0X001518.hg
Z68129_cds1_at
g4758581_3p_a_at
Participates
as a component of
IDH3 complex [mitochondrial matrix] (Homo sapiens)
Other forms of this molecule
IDH3G(1-393) [mitochondrial intermembrane space]
IDH3G(1-393) [cytosol]
Inferred To
Idh3g [mitochondrial matrix]
(Drosophila melanogaster)
Idh3g [mitochondrial matrix]
(Mus musculus)
Idh3g [mitochondrial matrix]
(Rattus norvegicus)
idhg-1 [mitochondrial matrix]
(Caenorhabditis elegans)
idhB [mitochondrial matrix]
(Dictyostelium discoideum)
idh1 [mitochondrial matrix]
(Schizosaccharomyces pombe)
IDH3G [mitochondrial matrix]
(Bos taurus)
IDH3G [mitochondrial matrix]
(Canis familiaris)
IDH3G [mitochondrial matrix]
(Sus scrofa)
IDH1 [mitochondrial matrix]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_004126.1
,
NP_777358.1
ENSEMBL
ENST00000217901
,
ENSP00000359110
,
ENSG00000067829
,
ENST00000370092
,
ENSP00000217901
OpenTargets
ENSG00000067829
GeneCards
IDH3G
HPA
ENSG00000067829-IDH3G
PRO
P51553
Pharos - Targets
P51553
GlyGen
P51553
HMDB Protein
HMDBP00900
PDB
8GRG
,
5GRH
,
5GRI
,
8GS5
,
8GRH
,
5GRL
,
5GRF
,
5GRE
,
7CE3
,
6L57
,
5YVT
,
6L59
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P10809 HSPD1
6
HSPD1 [mitochondrial inner membrane]
(R-HSA-1299455)
HSPD1 [mitochondrial matrix]
(R-HSA-1299448)
HSPD1(1-573) [mitochondrial inner membrane]
(R-HSA-1299442)
HSPD1(1-26) [mitochondrial matrix]
(R-HSA-8986171)
HSPD1(1-573) [mitochondrial intermembrane space]
(R-HSA-1267963)
HSPD1(1-573) [cytosol]
(R-HSA-1267989)
0.641
3
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