Reactome | PDH complex [mitochondrial matrix]

Stable Identifier

R-HSA-70070

Type

Complex

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

pyruvate dehydrogenase complex

GO Cellular Component

pyruvate dehydrogenase complex (0045254)

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
2188967	Structure-function relationships in dihydrolipoamide acyltransferases. Reed, LJ, Hackert, ML	J Biol Chem	1990
9242632	Dihydrolipoamide dehydrogenase-binding protein of the human pyruvate dehydrogenase complex. DNA-derived amino acid sequence, expression, and reconstitution of the pyruvate dehydrogenase complex. Harris, RA, Bowker-Kinley, MM, Wu, P, Jeng, J, Popov, KM	J Biol Chem	1997
11752427	The remarkable structural and functional organization of the eukaryotic pyruvate dehydrogenase complexes. Zhou, ZH, McCarthy, DB, O'Connor, CM, Reed, LJ, Stoops, JK	Proc Natl Acad Sci U S A	2001
10679936	Mutations in the X-linked pyruvate dehydrogenase (E1) alpha subunit gene (PDHA1) in patients with a pyruvate dehydrogenase complex deficiency Lissens, W, De Meirleir, L, Seneca, S, Liebaers, I, Brown, GK, Brown, RM, Ito, M, Naito, E, Kuroda, Y, Kerr, DS, Wexler, ID, Patel, MS, Robinson, BH, Seyda, A	Hum Mutat	2000
11935326	Pyruvate dehydrogenase E3 binding protein deficiency. Brown, RM, Head, RA, Brown, GK	Hum Genet	2002