Ubiquitination of phosphorylated Cdc25A

Stable Identifier
R-HSA-69598
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Ubiquitination of phosphorylated Cdc25A
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At the beginning of this reaction, 1 molecule of 'ubiquitin', and 1 molecule of 'phospho-Cdc25A' are present. At the end of this reaction, 1 molecule of 'Ubiquitinated Phospho-Cdc25A' is present.

This reaction takes place in the 'cytosol' and is mediated by the 'ubiquitin-protein ligase activity' of 'Ubiquitin ligase' (Bernardi et al. 2000).
Literature References
PubMed ID Title Journal Year
10828887 Cdc25A stability is controlled by the ubiquitin-proteasome pathway during cell cycle progression and terminal differentiation

Bernardi, R, Hoffman, B, Liebermann, DA

Oncogene 2000
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Catalyst Activity

ubiquitin-protein transferase activity of Ubiquitin ligase [cytosol]

Physical Entity
Ubiquitin ligase [cytosol] (Homo sapiens)
Activity
ubiquitin-protein transferase activity (GO:0004842)
Created
Hoffmann, I  (2003-06-05)
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