Ubiquitinated Cdc6 is degraded by the proteasome

Stable Identifier
R-HSA-69016
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Ubiquitinated Cdc6 is degraded by the proteasome
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of 'ubiquitinated Cdc6' is present. At the end of this reaction, 1 molecule of 'ubiquitin' is present.

This reaction takes place in the 'cytosol' and is mediated by the 'endopeptidase activity' of '26S proteasome'.
Literature References
Participants
Input
Output
Participates
as an event of
Catalyst Activity

endopeptidase activity of 26S proteasome [cytosol]

Physical Entity
26S proteasome [cytosol] (Homo sapiens)
Activity
endopeptidase activity (GO:0004175)
Orthologous Events
Ubiquitinated Cdc6 is degraded by the proteasome (Bos taurus)
Ubiquitinated Cdc6 is degraded by the proteasome (Caenorhabditis elegans)
Ubiquitinated Cdc6 is degraded by the proteasome (Canis familiaris)
Ubiquitinated Cdc6 is degraded by the proteasome (Danio rerio)
Ubiquitinated Cdc6 is degraded by the proteasome (Dictyostelium discoideum)
Ubiquitinated Cdc6 is degraded by the proteasome (Drosophila melanogaster)
Ubiquitinated Cdc6 is degraded by the proteasome (Gallus gallus)
Ubiquitinated Cdc6 is degraded by the proteasome (Mus musculus)
Ubiquitinated Cdc6 is degraded by the proteasome (Plasmodium falciparum)
Ubiquitinated Cdc6 is degraded by the proteasome (Rattus norvegicus)
Ubiquitinated Cdc6 is degraded by the proteasome (Saccharomyces cerevisiae)
Ubiquitinated Cdc6 is degraded by the proteasome (Schizosaccharomyces pombe)
Ubiquitinated Cdc6 is degraded by the proteasome (Sus scrofa)
Ubiquitinated Cdc6 is degraded by the proteasome (Xenopus tropicalis)
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