Reactome | KRTAP5-2 [cytosol]

KRTAP5-2 [cytosol]

Stable Identifier

R-HSA-6810291

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 5-2, KRA52_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP5s [cytosol] (Homo sapiens)
        
        KRTAP5-2 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP5s [cytosol] (Homo sapiens)
        
        KRTAP5-2 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q701N4 KRTAP5-2

Gene Names

KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8

Chain

chain:1-177

Reference Genes

BioGPS Gene:440021 KRTAP5-2

COSMIC - genes:KRTAP5-2 KRTAP5-2

COSMIC - genes:KRTAP5-8 KRTAP5-8

CTD Gene:440021 KRTAP5-2

dbSNP Gene:440021 KRTAP5-2

ENSEMBL:ENSG00000205867 KRTAP5-2

HGNC:23597 KRTAP5-2

KEGG:hsa:440021 KRTAP5-2

Monarch:440021 KRTAP5-2

NCBI Gene:440021 KRTAP5-2

UCSC:Q701N4 KRTAP5-2

Reference Transcript

RefSeq:NM_001004325.2 KRTAP5-2

Other Identifiers

11735638_a_at

11735639_x_at

11750368_a_at

11750369_x_at

16734284

3316967

3316994

3339038

3358898

3358899

3358900

3358901

3358902

3358903

3358905

3358913

3358923

440021

7945648

A_33_P3364373

GO:0005515

GO:0005829

GO:0005882

HMNXSV003021500

ILMN_1802360

TC11001262.hg

TC11002991.hg

Participates

as a member of

KRTAP5s [cytosol] (Homo sapiens)

Inferred To

Krtap5-2 [cytosol] (Mus musculus)

Krtap5-1 [cytosol] (Mus musculus)

Gm10153 [cytosol] (Mus musculus)

Krtap5-24 [cytosol] (Mus musculus)

Krtap5-8 [cytosol] (Rattus norvegicus)

Gm4553 [cytosol] (Mus musculus)

Krtap5-23 [cytosol] (Mus musculus)

Krtap5-22 [cytosol] (Mus musculus)

Krtap5-25 [cytosol] (Mus musculus)

Krtap5-4 [cytosol] (Mus musculus)

Krtap5-21 [cytosol] (Mus musculus)

Homologues of KRTAP5-2 [cytosol] (Mus musculus)

Krtap5-20 [cytosol] (Mus musculus)

Krtap5-26 [cytosol] (Mus musculus)

Krtap5-5 [cytosol] (Mus musculus)

Cross References

RefSeq

NP_001004325.1

ENSEMBL

ENST00000707559, ENST00000612541, ENSG00000281533, ENSP00000516912, ENSP00000484511, ENST00000412090, ENSP00000487099, ENSG00000278489, ENSP00000400041, ENSG00000291434, ENSG00000205867, ENST00000628787

OpenTargets

ENSG00000205867

GeneCards

KRTAP5-2

HPA

ENSG00000205867-KRTAP5-2

PRO

Q701N4

Pharos - Targets

Q701N4

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	5
UniProt:Q49AN0 CRY2	5	CRY2 [cytosol] (R-HSA-400255) p-S-CRY2 [nucleoplasm] (R-HSA-400328) p-S-CRY2 [cytosol] (R-HSA-400305) K48polyUb-K126,p-S-CRY2 [cytosol] (R-HSA-9932882) K48polyUb-K,p-S-CRY2 [nucleoplasm] (R-HSA-517935)	0.556	3
UniProt:P07438 MT1B	1	MT1B [cytosol] (R-HSA-5660371)	0.556	3
UniProt:Q86YT5 SLC13A5	1	SLC13A5 [plasma membrane] (R-HSA-433135)	0.556	3

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