Reactome | KRTAP4-7 [cytosol]

KRTAP4-7 [cytosol]

Stable Identifier

R-HSA-6809963

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 4-7, KRA47_HUMAN

Locations in the PathwayBrowser

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Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP4s [cytosol] (Homo sapiens)
        
        KRTAP4-7 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP4s [cytosol] (Homo sapiens)
        
        KRTAP4-7 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9BYR0 KRTAP4-7

Gene Names

KRTAP4-7, KAP4.7, KRTAP4.7

Chain

chain:1-210

Reference Genes

COSMIC (genes):KRTAP4-7 KRTAP4-7

ENSEMBL:ENSG00000240871 KRTAP4-7

ENSEMBL:ENSG00000240871.7 KRTAP4-7

HGNC:18898 KRTAP4-7

UCSC:Q9BYR0 KRTAP4-7

Reference Transcript

RefSeq:XM_003846478.1 KRTAP4-7

Other Identifiers

100132476

11742373_s_at

16834124

216810_PM_at

216810_at

3721188

3721189

3721190

3721191

3721192

3721193

3721194

3721199

3721200

3721203

3756734

3756743

3756753

3756763

3756774

8007112

8007115

8015218

8015221

8015230

8019699

A_14_P120027

A_23_P66844

A_33_P3256257

A_33_P3317752

GE742380

GO:0005515

GO:0005829

GO:0005856

GO:0005882

GO:0042633

GO:0043226

GO:0045095

HMNXSV003015262

Hs.307020.0.S1_3p_at

ILMN_1680432

ILMN_1718202

PH_hs_0033007

Participates

as a member of

KRTAP4s [cytosol] (Homo sapiens)

Inferred To

LOC104968477 [cytosol] (Bos taurus)

ENSRNOG00000068861 [cytosol] (Rattus norvegicus)

KRTAP4-7 [cytosol] (Bos taurus)

KRTAP4-7 [cytosol] (Canis familiaris)

KRTAP4-7 [cytosol] (Sus scrofa)

KRTAP4-7 [cytosol] (Xenopus tropicalis)

LOC100848612 [cytosol] (Bos taurus)

LOC787051 [cytosol] (Bos taurus)

Homologues of KRTAP4-7 [cytosol] (Bos taurus)

Homologues of KRTAP4-7 [cytosol] (Sus scrofa)

Homologues of KRTAP4-7 [cytosol] (Xenopus tropicalis)

LOC100848572 [cytosol] (Bos taurus)

Krtap4-13 [cytosol] (Mus musculus)

Cross References

RefSeq

XP_003846526.1

OpenTargets

ENSG00000240871

GeneCards

Q9BYR0

HPA

ENSG00000240871-KRTAP4-7

Ensembl

ENSP00000375236, ENST00000391417, ENSG00000240871

PRO

Q9BYR0

Pharos - Targets

Q9BYR0

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43597 SPRY2	8	p-S111,S120-SPRY2 [cytosol] (R-HSA-1295590) p-Y55-SPRY2 [cytosol] (R-HSA-182950) SPRY2 [plasma membrane] (R-HSA-182924) SPRY2 [cytosol] (R-HSA-182949) p-S112,S115-SPRY2 [cytosol] (R-HSA-1295619) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-934555) p-S112,S121-SPRY2 [plasma membrane] (R-HSA-934595) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-1295629)	0.556	3
UniProt:O76003 GLRX3	1	GLRX3 [cytosol] (R-HSA-5691202)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3

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