PECR associated with the peroxisomal membrane catalyzes the NADPH-dependent reduction of 2E-phytenoyl-CoA to form phytanoyl-CoA (Das et al. 2000; Gloerich et al. 2006). The active form of the enzyme is inferred to be a homotetramer from unpublished data deposited in PDB (accession 1YXM). This reaction is part of the process by which dietary phytol, ultimately derived from chlorophyll, is catabolized (Van Veldhoven 2010).
van den Brink, DM
Van Veldhoven, PP
trans-2-enoyl-CoA reductase (NADPH) activity of PECR tetramer [peroxisomal membrane]