Reactome | COTL1 [extracellular region]

COTL1 [extracellular region]

Stable Identifier

R-HSA-6806475

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Coactosin-like protein, COTL1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q14019 COTL1

Gene Names

COTL1, CLP

Chain

initiator methionine:, chain:2-142

Reference Genes

BioGPS Gene:23406 COTL1

COSMIC (genes):COTL1 COTL1

CTD Gene:23406 COTL1

dbSNP Gene:23406 COTL1

ENSEMBL:ENSG00000103187 COTL1

ENSEMBL_homo_sapiens_GENE:ENSG00000103187.8 COTL1

HGNC:18304 COTL1

KEGG Gene (Homo sapiens):23406 COTL1

Monarch:23406 COTL1

NCBI Gene:23406 COTL1

OMIM:606748 COTL1

UCSC:Q14019 COTL1

Reference Transcript

RefSeq:NM_021149.3 COTL1

Other Identifiers

11715524_a_at

11754124_a_at

11754125_x_at

16828826

221059_PM_s_at

221059_s_at

224583_PM_at

224583_at

23406

3702548

3702549

3702550

3702572

3702583

3702585

3702586

57171_at

8003171

A_23_P3866

A_23_P83624

A_24_P416131

GE78975

GO:0003779

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005829

GO:0005856

GO:0005884

GO:0007010

GO:0008092

GO:0008150

GO:0019899

GO:0030427

GO:0030833

GO:0030864

GO:0031410

GO:0034774

GO:0043226

GO:0050832

GO:0051015

GO:0065003

GO:0070062

GO:0098542

GO:1904813

HMNXSV003025874

Hs.289092.0.S1_3p_s_at

ILMN_1788283

PH_hs_0029645

TC16001314.hg

Participates

as a member of

Other forms of this molecule

COTL1 [secretory granule lumen]

COTL1 [ficolin-1-rich granule lumen]

Inferred To

cotl1 [extracellular region] (Danio rerio)

Cotl1 [extracellular region] (Mus musculus)

Cotl1 [extracellular region] (Rattus norvegicus)

COTL1 [extracellular region] (Bos taurus)

COTL1 [extracellular region] (Canis familiaris)

COTL1 [extracellular region] (Dictyostelium discoideum)

COTL1 [extracellular region] (Gallus gallus)

COTL1 [extracellular region] (Sus scrofa)

Homologues of COTL1 [extracellular region] (Dictyostelium discoideum)

abpE-2 [extracellular region] (Dictyostelium discoideum)

Dmel\CG6891 [extracellular region] (Drosophila melanogaster)

Cross References

RefSeq

NP_066972.1

OpenTargets

ENSG00000103187

HPA

ENSG00000103187-COTL1

GeneCards

Q14019

Ensembl

ENST00000262428, ENSG00000103187, ENSP00000262428

PRO

Q14019

Pharos - Targets

Q14019

HMDB Protein

HMDBP07619

PDB

1T2L, 1WNJ, 1TMW, 1VFQ, 1T3X, 1T3Y

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P09917 ALOX5	6	p-S272-ALOX5 [cytosol] (R-HSA-265276) ALOX5 [secretory granule lumen] (R-HSA-6801306) ALOX5 [extracellular region] (R-HSA-6806468) ALOX5 [ficolin-1-rich granule lumen] (R-HSA-6801302) ALOX5 [cytosol] (R-HSA-429010) p-S272-ALOX5 [nuclear envelope] (R-HSA-2318765)	0.698	5

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