Reactome | AGL [extracellular region]

AGL [extracellular region]

Stable Identifier

R-HSA-6806460

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

glycogen debranching enzyme, glycogen debrancher, GDE_HUMAN, Glycogen debranching enzyme, Glycogen debrancher, 4-alpha- glucanotransferase , Oligo-1,4-1,4-glucantransferase, Amylo-alpha-1,6-glucosidase , Amylo-1,6-glucosidase, Dextrin 6-alpha-D-glucosidase

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
2961257	Glycogen debranching enzyme: purification, antibody characterization, and immunoblot analyses of type III glycogen storage disease. Ding, JH, Brown, BI, Chen, Y-T, He, JK	Am J Hum Genet	1988
8755644	Mutations in exon 3 of the glycogen debranching enzyme gene are associated with glycogen storage disease type III that is differentially expressed in liver and muscle. Chen, Y-T, Lee, P, Leonard, JV, Bao, Y, Liu, HM, Shen, J	J Clin Invest	1996

External Reference Information

External Reference

UniProt:P35573 AGL

Gene Names

AGL, GDE

Chain

chain:1-1532

Reference Genes

BioGPS Gene:178 AGL

COSMIC (genes):AGL AGL

CTD Gene:178 AGL

dbSNP Gene:178 AGL

ENSEMBL:ENSG00000162688 AGL

HGNC:321 AGL

KEGG Gene (Homo sapiens):178 AGL

Monarch:178 AGL

NCBI Gene:178 AGL

OMIM:610860 AGL

UCSC:P35573 AGL

Reference Transcript

Other Identifiers

0001740471

0002060180

0005720739

11720888_s_at

11720889_a_at

11720890_a_at

16667546

178

203566_PM_s_at

203566_s_at

2348635

2348636

2348637

2348638

2348639

2348640

2348641

2348644

2348645

2348646

2348647

2348649

2348650

2348652

2348653

2348654

2348655

2348656

2348657

2348658

2348659

2348660

2348661

2348662

2348663

2348665

2348668

2348669

2348670

2348671

2348673

2348674

2348675

2348677

2348679

2348680

2348681

2348683

2348684

2348686

2348688

2348689

2348690

2348692

2348693

38252_s_at

38253_at

7903239

A_14_P130836

A_23_P200298

GO:0003674

GO:0003824

GO:0004133

GO:0004134

GO:0004135

GO:0005515

GO:0005575

GO:0005576

GO:0005622

GO:0005634

GO:0005737

GO:0005783

GO:0005829

GO:0005975

GO:0005977

GO:0005978

GO:0005980

GO:0006091

GO:0007584

GO:0008150

GO:0008152

GO:0009056

GO:0009058

GO:0009725

GO:0016234

GO:0016529

GO:0016740

GO:0016757

GO:0016787

GO:0016798

GO:0030246

GO:0030247

GO:0031410

GO:0031593

GO:0032991

GO:0034774

GO:0043033

GO:0043226

GO:0051384

GO:0102500

GO:1904813

HMNXSV003007471

ILMN_1664006

ILMN_1680343

ILMN_1717468

ILMN_2277492

ILMN_2371825

PH_hs_0000112

TC01000895.hg

U84011_s_at

g4557282_3p_a_at

Participates

as a member of

Other forms of this molecule

AGL [secretory granule lumen]

AGL [ficolin-1-rich granule lumen]

AGL [cytosol]

Inferred To

GDB1 [extracellular region] (Saccharomyces cerevisiae)

AGL [extracellular region] (Bos taurus)

AGL [extracellular region] (Canis familiaris)

AGL [extracellular region] (Dictyostelium discoideum)

AGL [extracellular region] (Gallus gallus)

AGL [extracellular region] (Sus scrofa)

agl [extracellular region] (Xenopus tropicalis)

BEST:GH22856 [extracellular region] (Drosophila melanogaster)

agla [extracellular region] (Danio rerio)

Agl [extracellular region] (Mus musculus)

Agl [extracellular region] (Rattus norvegicus)

agl-1 [extracellular region] (Caenorhabditis elegans)

Cross References

RefSeq

NP_000019.2, NP_000635.2, NP_000633.2, XP_005270614.1, NP_000637.2, NP_000634.2

ZINC - World Drugs

GDE_HUMAN

OpenTargets

ENSG00000162688

ZINC - FDA approved

GDE_HUMAN

ZINC - Substances

GDE_HUMAN

ZINC target

P35573

ZINC - Biogenic

GDE_HUMAN

PRO

P35573

ZINC - Metabolites

GDE_HUMAN

HPA

ENSG00000162688-AGL

GeneCards

P35573

Ensembl

ENSP00000359182, ENST00000361915, ENSP00000359180, ENST00000370161, ENSP00000294724, ENSG00000162688, ENST00000370163, ENSP00000359184, ENSP00000355106, ENST00000370165, ENST00000294724

Pharos - Targets

P35573

ZINC - Predictions - Purchasable

GDE_HUMAN

Orphanet

15472

HMDB Protein

HMDBP00367