TP53 stimulates FANCC expression

Stable Identifier
R-HSA-6806425
Type
Reaction [omitted]
Species
Homo sapiens
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TP53 (p53) stimulates transcription of the FANCC (Fanconi anemia group C) gene, involved in the Fanconi anemia pathway that repairs DNA interstrand crosslinks, by binding to the p53 response element in the FANCC promoter (Liebetrau et al. 1997).

Literature References
PubMed ID Title Journal Year
9063748 p53 activates Fanconi anemia group C gene expression

Liebetrau, W, Budde, A, Savoia, A, Grummt, F, Hoehn, H

Hum. Mol. Genet. 1997
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