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MTHFD2L [mitochondrial matrix]
Stable Identifier
R-HSA-6801350
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, MTD2L_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Metabolism of folate and pterines (Homo sapiens)
MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Homo sapiens)
MTHFD2, D2L [mitochondrial matrix] (Homo sapiens)
MTHFD2L [mitochondrial matrix] (Homo sapiens)
MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF (Homo sapiens)
MTHFD2, D2L [mitochondrial matrix] (Homo sapiens)
MTHFD2L [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H903 MTHFD2L
Gene Names
MTHFD2L
Chain
chain:1-347
Reference Genes
BioGPS Gene:441024 MTHFD2L
COSMIC (genes):MTHFD2L MTHFD2L
CTD Gene:441024 MTHFD2L
dbSNP Gene:441024 MTHFD2L
ENSEMBL:ENSG00000163738 MTHFD2L
HGNC:31865 MTHFD2L
KEGG:hsa:441024 MTHFD2L
Monarch:441024 MTHFD2L
NCBI Gene:441024 MTHFD2L
OMIM:614047 MTHFD2L
UCSC:Q9H903 MTHFD2L
Reference Transcript
RefSeq:XM_054350075.1 MTHFD2L
RefSeq:NM_001004346.4 MTHFD2L
RefSeq:XM_017008219.3 MTHFD2L
RefSeq:NM_001144978.3 MTHFD2L
RefSeq:XM_047415715.1 MTHFD2L
Other Identifiers
11740964_a_at
11753047_a_at
11762057_at
11762572_x_at
1554841_PM_at
1554841_at
1562644_PM_at
1562644_at
16967801
220346_PM_at
220346_at
233083_3p_at
233083_PM_at
233083_at
238762_PM_at
238762_at
239562_PM_at
239562_at
242370_PM_at
242370_at
2731418
2731419
2731420
2731421
2731422
2731424
2731425
2731428
2731429
2731430
2731431
2731432
2731438
2731439
2731440
2731441
2731443
2731444
2731445
2731447
2731448
2731450
2731451
2731452
2731454
2731455
2731456
2731457
2731459
2731460
2731469
2731470
2731476
2731479
2731480
2731482
2731487
2731488
2731489
2731490
42461_at
441024
62230_at
78991_at
8095705
91764_s_at
A_23_P112846
A_24_P307314
A_33_P3366258
GE83038
GO:0000105
GO:0003824
GO:0004477
GO:0004487
GO:0004488
GO:0005515
GO:0005739
GO:0005743
GO:0005759
GO:0006164
GO:0006520
GO:0006575
GO:0006730
GO:0006766
GO:0006790
GO:0009086
GO:0009256
GO:0016491
GO:0016787
GO:0035999
GO:0043226
GO:0046655
GO:0055086
HMNXSV003049161
HMNXSV003050205
Hs.105094.1.A1_3p_at
Hs.136330.0.A1_3p_at
Hs.154894.0.A1_3p_at
Hs2.375093.1.S1_3p_at
Hs2.407156.1.S1_3p_at
ILMN_1652434
PH_hs_0039740
g13376512_3p_at
Participates
as a member of
MTHFD2, D2L [mitochondrial matrix] (Homo sapiens)
Inferred To
Mthfd2l [mitochondrial matrix]
(Mus musculus)
Mthfd2l [mitochondrial matrix]
(Rattus norvegicus)
mthfd2l [mitochondrial matrix]
(Xenopus tropicalis)
ADE3 [mitochondrial matrix]
(Saccharomyces cerevisiae)
MTHFD2L [mitochondrial matrix]
(Bos taurus)
MTHFD2L [mitochondrial matrix]
(Canis familiaris)
MTHFD2L [mitochondrial matrix]
(Dictyostelium discoideum)
MTHFD2L [mitochondrial matrix]
(Gallus gallus)
MTHFD2L [mitochondrial matrix]
(Plasmodium falciparum)
MTHFD2L [mitochondrial matrix]
(Schizosaccharomyces pombe)
MTHFD2L [mitochondrial matrix]
(Sus scrofa)
MIS1 [mitochondrial matrix]
(Saccharomyces cerevisiae)
Homologues of MTHFD2L [mitochondrial matrix]
(Dictyostelium discoideum)
Homologues of MTHFD2L [mitochondrial matrix]
(Saccharomyces cerevisiae)
Homologues of MTHFD2L [mitochondrial matrix]
(Schizosaccharomyces pombe)
ade9 [mitochondrial matrix]
(Schizosaccharomyces pombe)
Nmdmc [mitochondrial matrix]
(Drosophila melanogaster)
Cross References
RefSeq
XP_016863708.2
,
NP_001004346.2
,
XP_047271671.1
,
XP_054206050.1
,
NP_001138450.1
ENSEMBL
ENSG00000163738
,
ENSP00000321984
,
ENST00000395759
,
ENST00000325278
,
ENSP00000379108
OpenTargets
ENSG00000163738
GeneCards
MTHFD2L
HPA
ENSG00000163738-MTHFD2L
PRO
Q9H903
Pharos - Targets
Q9H903
HMDB Protein
HMDBP07262
PDB
7QEI
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5T8I9 HENMT1
1
HENMT1 [cytosol]
(R-HSA-5601916)
0.527
2
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