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MTHFS [cytosol]
Stable Identifier
R-HSA-6801331
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
5-formyltetrahydrofolate cyclo-ligase ecNumber6.3.3.2/ecNumber, MTHFS_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Metabolism of folate and pterines (Homo sapiens)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Homo sapiens)
MTHFS [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P49914 MTHFS
Gene Names
MTHFS
Chain
initiator methionine:, chain:2-203
Reference Genes
BioGPS Gene:10588 MTHFS
COSMIC (genes):MTHFS MTHFS
CTD Gene:10588 MTHFS
dbSNP Gene:10588 MTHFS
ENSEMBL:ENSG00000136371 MTHFS
HGNC:7437 MTHFS
KEGG:hsa:10588 MTHFS
Monarch:10588 MTHFS
NCBI Gene:10588 MTHFS
OMIM:604197 MTHFS
UCSC:P49914 MTHFS
Reference Transcript
RefSeq:NM_001199758.1 MTHFS
RefSeq:NM_006441.3 MTHFS
Other Identifiers
10588
11722404_s_at
1559069_PM_at
1559069_at
203433_PM_at
203433_at
3635126
3635127
3635128
3635129
3635130
3635131
3635132
3635133
3635146
3635147
3635148
3635151
3635152
3635154
3635155
39064_at
7990810
86183_at
A_23_P163380
GE498156
GE57751
GO:0003824
GO:0005515
GO:0005524
GO:0005542
GO:0005737
GO:0005739
GO:0005759
GO:0005829
GO:0006520
GO:0006536
GO:0006575
GO:0006766
GO:0009396
GO:0015942
GO:0016874
GO:0030272
GO:0035999
GO:0043226
GO:0046653
GO:0046655
GO:0046657
GO:0046872
HMNXSV003033042
Hs2.194294.1.S1_3p_at
ILMN_1772302
ILMN_1822559
L38928_at
PH_hs_0006488
PH_hs_0011470
TC15002651.hg
TC15002780.hg
g5453745_3p_at
p25938
Inferred To
MTHFS [cytosol]
(Bos taurus)
MTHFS [cytosol]
(Caenorhabditis elegans)
MTHFS [cytosol]
(Canis familiaris)
MTHFS [cytosol]
(Danio rerio)
MTHFS [cytosol]
(Drosophila melanogaster)
MTHFS [cytosol]
(Gallus gallus)
MTHFS [cytosol]
(Mus musculus)
MTHFS [cytosol]
(Plasmodium falciparum)
MTHFS [cytosol]
(Saccharomyces cerevisiae)
MTHFS [cytosol]
(Schizosaccharomyces pombe)
MTHFS [cytosol]
(Sus scrofa)
MTHFS [cytosol]
(Xenopus tropicalis)
Homologues of MTHFS [cytosol]
(Mus musculus)
Mthfs [cytosol]
(Rattus norvegicus)
Cross References
ENSEMBL
ENST00000258874
,
ENSP00000258874
,
ENSG00000136371
OpenTargets
ENSG00000136371
GeneCards
MTHFS
HPA
ENSG00000136371-MTHFS
PRO
P49914
Pharos - Targets
P49914
Orphanet
MTHFS
HMDB Protein
HMDBP01408
PDB
3HXT
,
3HY4
,
3HY6
,
3HY3
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UPR0 PLCL2
0.589
2
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