Reactome | PTX3 [tertiary granule lumen]

PTX3 [tertiary granule lumen]

Stable Identifier

R-HSA-6800932

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

tertiary granule lumen

Synonyms

Pentraxin-related protein PTX3, PTX3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P26022 PTX3

Gene Names

PTX3, TNFAIP5, TSG14

Chain

signal peptide:1-17, chain:18-381

Reference Genes

BioGPS Gene:5806 PTX3

COSMIC (genes):PTX3 PTX3

CTD Gene:5806 PTX3

dbSNP Gene:5806 PTX3

ENSEMBL:ENSG00000163661 PTX3

HGNC:9692 PTX3

KEGG:hsa:5806 PTX3

Monarch:5806 PTX3

NCBI Gene:5806 PTX3

OMIM:602492 PTX3

UCSC:P26022 PTX3

Reference Transcript

RefSeq:NM_002852.3 PTX3

Participates

as a member of

Tertiary granule lumen proteins [tertiary granule lumen] (Homo sapiens)

Other forms of this molecule

PTX3 [specific granule lumen]

PTX3 [extracellular region]

Inferred To

ptx3 [tertiary granule lumen] (Xenopus tropicalis)

Ptx3 [tertiary granule lumen] (Mus musculus)

Ptx3 [tertiary granule lumen] (Rattus norvegicus)

PTX3 [tertiary granule lumen] (Bos taurus)

PTX3 [tertiary granule lumen] (Canis familiaris)

PTX3 [tertiary granule lumen] (Gallus gallus)

PTX3 [tertiary granule lumen] (Sus scrofa)

Cross References

ENSEMBL

ENST00000295927, ENSP00000295927, ENSG00000163661

OpenTargets

ENSG00000163661

GeneCards

PTX3

HPA

ENSG00000163661-PTX3

PRO

P26022

Pharos - Targets

P26022

PDB

7ZL1, 8PVQ

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P09038 FGF2	1	FGF2(10-155) [extracellular region] (R-HSA-189898)	0.788	16
UniProt:P08603 CFH	1	CFH [extracellular region] (R-HSA-976788)	0.734	15
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) p-11S,2T-N [cytosol] (R-COV-9729264) p-8S,2T-N [cytosol] (R-COV-9729277) p-8S-N [cytosol] (R-COV-9729335) p-S188,206-N [cytosol] (R-COV-9729324) N [cytosol] (R-COV-9694300) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [plasma membrane] (R-COV-9694356) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325)	0.558	2

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