Reactome | MAN2B2 [lysosomal lumen]

MAN2B2 [lysosomal lumen]

Stable Identifier

R-HSA-6799575

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal lumen

Synonyms

Epididymis-specific alpha-mannosidase ecNumber3.2.1.24/ecNumber, MA2B2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y2E5 MAN2B2

Gene Names

MAN2B2, KIAA0935

Chain

signal peptide:1-23, chain:24-1009

Reference Genes

BioGPS Gene:23324 MAN2B2

COSMIC (genes):MAN2B2 MAN2B2

CTD Gene:23324 MAN2B2

dbSNP Gene:23324 MAN2B2

ENSEMBL:ENSG00000013288 MAN2B2

HGNC:29623 MAN2B2

KEGG:hsa:23324 MAN2B2

Monarch:23324 MAN2B2

NCBI Gene:23324 MAN2B2

OMIM:618899 MAN2B2

UCSC:Q9Y2E5 MAN2B2

Reference Transcript

Other Identifiers

11727979_a_at

11752109_a_at

11758992_at

16964695

214703_3p_s_at

214703_PM_s_at

214703_s_at

23324

2717015

2717018

2717019

2717022

2717023

2717024

2717025

2717026

2717027

2717028

2717029

2717031

2717032

2717033

2717034

2717035

2717036

2717037

2717038

2717039

2717040

2717041

2717042

2717043

2717044

2717045

2717046

2717047

39369_at

8093916

A_23_P250379

GE53609

GO:0003824

GO:0004559

GO:0005515

GO:0005576

GO:0005764

GO:0005773

GO:0005975

GO:0006013

GO:0009313

GO:0016787

GO:0016798

GO:0030246

GO:0043202

GO:0043226

GO:0046872

GO:0070062

HMNXSV003040487

HMNXSV003042193

Hs.303394.0.S1_3p_s_at

ILMN_1768510

PH_hs_0022974

PH_hs_0040447

TC04000069.hg

Participates

as a component of

MAN2B2:Zn2+ [lysosomal lumen] (Homo sapiens)

Inferred To

LManVI [lysosomal lumen] (Drosophila melanogaster)

Man2b2 [lysosomal lumen] (Rattus norvegicus)

aman-1 [lysosomal lumen] (Caenorhabditis elegans)

LManIV [lysosomal lumen] (Drosophila melanogaster)

man2b2 [lysosomal lumen] (Xenopus tropicalis)

LManI [lysosomal lumen] (Drosophila melanogaster)

LManII [lysosomal lumen] (Drosophila melanogaster)

LManIII [lysosomal lumen] (Drosophila melanogaster)

Homologues of MAN2B2 [lysosomal lumen] (Dictyostelium discoideum)

Homologues of MAN2B2 [lysosomal lumen] (Drosophila melanogaster)

LManV [lysosomal lumen] (Drosophila melanogaster)

MAN2B2 [lysosomal lumen] (Bos taurus)

MAN2B2 [lysosomal lumen] (Dictyostelium discoideum)

MAN2B2 [lysosomal lumen] (Gallus gallus)

MAN2B2 [lysosomal lumen] (Mus musculus)

MAN2B2 [lysosomal lumen] (Sus scrofa)

Cross References

ENSEMBL

ENST00000285599, ENSP00000285599

OpenTargets

ENSG00000013288

IntEnz

3.2.1.24

HPA

ENSG00000013288-MAN2B2

ZINC - Substances

MA2B2_HUMAN

ZINC target

Q9Y2E5

PRO

Q9Y2E5

Pharos - Targets

Q9Y2E5

GlyGen

Q9Y2E5

HMDB Protein

HMDBP11811

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.556	3

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