Exocytosis of secretory granule lumen proteins

Stable Identifier
R-HSA-6798748
Type
Reaction [transition]
Species
Homo sapiens
Compartment
secretory granule lumen, extracellular region
ReviewStatus
5/5
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Exocytosis of secretory granule lumen proteins
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Secretory vesicles provide a reservoir of secreted proteins and membrane-associated receptors that are required at the earliest stages of the neutrophil-mediated inflammatory response. They are mobilized in response to a wide variety of inflammatory stimuli (Sengelov et al. 1993a,b). Resultant cell surface changes allow the neutrophil to establish firm contact with activated vascular epithelium (Faurschou & Borregaard 2003).
Literature References
PubMed ID Title Journal Year
23650620 Proteome profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane: correlation with transcriptome profiling of neutrophil precursors

Heegaard, NH, Rørvig, S, Borregaard, N, Østergaard, O

J. Leukoc. Biol. 2013
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Orthologous Events
Exocytosis of secretory granule lumen proteins (Bos taurus)
Exocytosis of secretory granule lumen proteins (Caenorhabditis elegans)
Exocytosis of secretory granule lumen proteins (Canis familiaris)
Exocytosis of secretory granule lumen proteins (Danio rerio)
Exocytosis of secretory granule lumen proteins (Dictyostelium discoideum)
Exocytosis of secretory granule lumen proteins (Drosophila melanogaster)
Exocytosis of secretory granule lumen proteins (Gallus gallus)
Exocytosis of secretory granule lumen proteins (Mus musculus)
Exocytosis of secretory granule lumen proteins (Plasmodium falciparum)
Exocytosis of secretory granule lumen proteins (Rattus norvegicus)
Exocytosis of secretory granule lumen proteins (Saccharomyces cerevisiae)
Exocytosis of secretory granule lumen proteins (Schizosaccharomyces pombe)
Exocytosis of secretory granule lumen proteins (Sus scrofa)
Exocytosis of secretory granule lumen proteins (Xenopus tropicalis)
Authored
Jupe, S  (2015-09-21)
Reviewed
Heegaard, N  (2016-06-13)
Created
Jupe, S  (2015-09-21)
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