TP53 stimulates E2F7 expression

Stable Identifier
R-HSA-6798299
Type
Reaction [omitted]
Species
Homo sapiens
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Binding of TP53 (p53) to the p53 response element in the promoter of the E2F7 gene stimulates E2F7 transcription (Carvajal et al. 2012, Aksoy et al. 2012).

Literature References
PubMed ID Title Journal Year
22802529 The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence

Aksoy, O, Chicas, A, Zeng, T, Zhao, Z, McCurrach, M, Wang, X, Lowe, SW

Genes Dev. 2012
22802528 E2F7, a novel target, is up-regulated by p53 and mediates DNA damage-dependent transcriptional repression

Carvajal, LA, Hamard, PJ, Tonnessen, C, Manfredi, JJ

Genes Dev. 2012
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