Reactome | LPPR4 [plasma membrane]

LPPR4 [plasma membrane]

Stable Identifier

R-HSA-6797623

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Lipid phosphate phosphatase-related protein type 4 ecNumber3.1.3.4/ecNumber, LPPR4_HUMAN

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR ligand binding (Homo sapiens)
    - Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
      - Lysosphingolipid and LPA receptors (Homo sapiens)
        
        LRPP4(LRPP1-3,5) hydrolyse LPA (Homo sapiens)
        
        LPPR4(LPPR1-3,5) [plasma membrane] (Homo sapiens)
        
        LPPR4 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q7Z2D5 PLPPR4

Gene Names

PLPPR4, KIAA0455, LPPR4, PHP1, PRG1

Chain

chain:1-763

Reference Genes

BioGPS Gene:9890 PLPPR4

COSMIC (genes):PLPPR4 PLPPR4

CTD Gene:9890 PLPPR4

dbSNP Gene:9890 PLPPR4

ENSEMBL:ENSG00000117600 PLPPR4

ENSEMBL_homo_sapiens_GENE:ENSG00000117600.14 PLPPR4

HGNC:23496 PLPPR4

KEGG Gene (Homo sapiens):9890 PLPPR4

Monarch:9890 PLPPR4

NCBI Gene:9890 PLPPR4

OMIM:607813 PLPPR4

UCSC:Q7Z2D5 PLPPR4

Reference Transcript

Other Identifiers

11721182_a_at

11721183_at

11752451_a_at

16667516

213496_PM_at

213496_at

2348515

2348516

2348517

2348518

2348526

2348527

2348528

2348531

2348532

2348533

2348534

2348535

2348536

2348537

2348538

41714_at

7903214

9890

A_32_P148538

A_33_P3384958

GE53196

GO:0003824

GO:0005886

GO:0006629

GO:0006644

GO:0007165

GO:0007186

GO:0007409

GO:0008195

GO:0016020

GO:0016787

GO:0023052

GO:0030154

GO:0043226

GO:0045202

GO:0045211

GO:0048839

GO:0048856

GO:0050804

GO:0051966

GO:0098839

GO:0098978

GO:0140354

HMNXSV003035618

Hs.13245.0.S1_3p_at

ILMN_1662482

ILMN_2172497

PH_hs_0001270

TC01000891.hg

Participates

as a member of

LPPR4(LPPR1-3,5) [plasma membrane] (Homo sapiens)

Inferred To

plppr4 [plasma membrane] (Xenopus tropicalis)

plpr-1 [plasma membrane] (Caenorhabditis elegans)

LPP1 [plasma membrane] (Saccharomyces cerevisiae)

DPP1 [plasma membrane] (Saccharomyces cerevisiae)

dpp1 [plasma membrane] (Schizosaccharomyces pombe)

LPPR4 [plasma membrane] (Dictyostelium discoideum)

Plppr4 [plasma membrane] (Mus musculus)

Plppr4 [plasma membrane] (Rattus norvegicus)

PLPPR4 [plasma membrane] (Bos taurus)

PLPPR4 [plasma membrane] (Canis familiaris)

PLPPR4 [plasma membrane] (Gallus gallus)

PLPPR4 [plasma membrane] (Sus scrofa)

Homologues of LPPR4 [plasma membrane] (Dictyostelium discoideum)

Homologues of LPPR4 [plasma membrane] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_001159724.1, NP_055654.2

OpenTargets

ENSG00000117600

HPA

ENSG00000117600-PLPPR4

GeneCards

Q7Z2D5

Ensembl

ENSP00000394913, ENSP00000359204, ENST00000370185, ENSG00000117600, ENST00000457765

PRO

Q7Z2D5

Pharos - Targets

Q7Z2D5

HMDB Protein

HMDBP07319

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