Disks large homolog proteins (DLGs, Post synaptic density proteins) 2, 3 and 4 interact with BEGAIN (Brain-enriched Guanylate Kinase-associated Protein) via their guanylate kinase-like (GK) domain. BEGAIN is specifically expressed in brain and enriched in the PSD fraction and may be involved in the organization of the components of synaptic junctions (Deguchi et al. 2001).
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