TP53 (p53) stimulates transcription of the ARID3A gene upon binding to the p53 response element in the second intron of the ARID3A gene (Ma et al. 2003). ARID3A is implicated as both a positive and a negative cell cycle regulator. It interacts with E2F1 and stimulates E2F1 transcriptional activity (Suzuki et al. 1998, Peeper et al. 2002). It may also cooperate with TP53 in the activation of CDKN1A (p21) transcription (Lestari et al. 2012).
Ikeda, MA, Ma, K, Suganuma, T, Tamamori-Adachi, M, Ichwan, SJ, Araki, K
Ikeda, MA, Otsu, M, Lestari, W, Yamada, S, Iseki, S, Ichwan, SJ, Shimizu, S
Douma, S, Shvarts, A, Koh, EY, Bernards, R, Daley, GQ, Brummelkamp, T, Peeper, DS
Oda, K, Okuyama, S, Shirasuna, K, Okamoto, S, Suzuki, M, Sekiya, S, Nakajima, T, Hachiya, T, Nojima, H
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