p-Y705-STAT3,p-Y641-STAT6 dissociate

Stable Identifier
R-HSA-6786072
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol, extracellular region, plasma membrane
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
p-Y705-STAT3,p-Y641-STAT6 dissociate
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Once phosphorylated, Signal transducer and activator of transcription 3 (STAT3) and STAT6 dissociate from the IL4 receptor/JAK1 complex.

Literature References
PubMed ID Title Journal Year
23124025 IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages

Bhattacharjee, A, Shukla, M, Yakubenko, VP, Mulya, A, Kundu, S, Cathcart, MK

Free Radic. Biol. Med. 2013
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
p-Y705-STAT3,p-Y641-STAT6 dissociate (Bos taurus)
p-Y705-STAT3,p-Y641-STAT6 dissociate (Canis familiaris)
p-Y705-STAT3,p-Y641-STAT6 dissociate (Danio rerio)
p-Y705-STAT3,p-Y641-STAT6 dissociate (Mus musculus)
p-Y705-STAT3,p-Y641-STAT6 dissociate (Rattus norvegicus)
p-Y705-STAT3,p-Y641-STAT6 dissociate (Xenopus tropicalis)
Authored
Jupe, S  (2015-07-01)
Reviewed
Leibovich, SJ  (2016-09-02)
Created
Jupe, S  (2015-07-03)