Expression of IL4, IL13-upregulated extracellular proteins

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R-HSA-6785895
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Reaction [omitted]
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Homo sapiens
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In human peripheral blood monocytes IL4 and IL13 significantly upregulate the levels of several extracellular proteins involved in inflammatory resolution including fibronectin (FN1), coagulation factor XIII (FXIII), annexin 1 (ANXA1), collagen type 1 alpha 2 (COL1A2), laminin alpha-5 (LAMA5) and C-C motif chemokine 22 (CCL22) (Chaitidis et al. 2005, Jinnin et al. 2004, Yakubenko et al. 2011).

Literature References
PubMed ID Title Journal Year
21252155 αMßâ‚‚ integrin activation prevents alternative activation of human and murine macrophages and impedes foam cell formation

Yakubenko, VP, Bhattacharjee, A, Pluskota, E, Cathcart, MK

Circ. Res. 2011
15869882 Gene expression alterations of human peripheral blood monocytes induced by medium-term treatment with the TH2-cytokines interleukin-4 and -13

Chaitidis, P, O'Donnell, V, Kuban, RJ, Bermudez-Fajardo, A, Ungethuem, U, Kühn, H

Cytokine 2005
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