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Ub-HIST1H2AC [nucleoplasm]
Stable Identifier
R-HSA-6782521
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
HIST1H2AC, Histone H2A.l
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Metalloprotease DUBs (Homo sapiens)
MYSM1 deubiquitinates Histone H2A (Homo sapiens)
MYSM1:EP300:KAT2B:Ub-histone H2A [nucleoplasm] (Homo sapiens)
Ub-histone H2A [nucleoplasm] (Homo sapiens)
Ub-histone HIST1 H2A [nucleoplasm] (Homo sapiens)
Ub-HIST1H2AC [nucleoplasm] (Homo sapiens)
UCH proteinases (Homo sapiens)
Histone H2A is dubiquitinated by the PR-DUB complex (Homo sapiens)
Ub-histone H2A [nucleoplasm] (Homo sapiens)
Ub-histone HIST1 H2A [nucleoplasm] (Homo sapiens)
Ub-HIST1H2AC [nucleoplasm] (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP16,USP21 deubiquitinate Histone H2A (Homo sapiens)
USP16,USP21:Ub-histone H2A [nucleoplasm] (Homo sapiens)
Ub-histone H2A [nucleoplasm] (Homo sapiens)
Ub-histone HIST1 H2A [nucleoplasm] (Homo sapiens)
Ub-HIST1H2AC [nucleoplasm] (Homo sapiens)
USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2A [nucleoplasm] (Homo sapiens)
Ub-histone HIST1 H2A [nucleoplasm] (Homo sapiens)
Ub-HIST1H2AC [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q93077 H2AC6
Gene Names
H2AC6, H2AFL, HIST1H2AC
Chain
initiator methionine:, chain:2-130
Reference Genes
BioGPS Gene:8334 H2AC6
CTD Gene:8334 H2AC6
dbSNP Gene:8334 H2AC6
ENSEMBL:ENSG00000180573 HIST1H2AC
ENSEMBL_homo_sapiens_GENE:ENSG00000180573.10 H2AC6
HGNC:4733 H2AC6
KEGG Gene (Homo sapiens):8334 H2AC6
Monarch:8334 H2AC6
NCBI Gene:8334 H2AC6
OMIM:602794 H2AC6
UCSC:Q93077 H2AC6
Reference Transcript
RefSeq:NM_003512.3 H2AC6
Other Identifiers
11736244_s_at
17005564
215071_PM_s_at
215071_s_at
2899153
2899154
2899155
2899156
2899167
2899168
2899169
2899170
34308_at
8117372
8334
ADDON002788.hg
A_14_P111416
A_14_P200165
A_23_P167983
A_23_P372860
A_33_P3344127
GE59543
GO:0000786
GO:0003674
GO:0003677
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005694
GO:0008285
GO:0030527
GO:0043226
GO:0043229
GO:0046982
GO:0070062
HMNXSV003001307
HMNXSV003032292
Hs.28777.3.A1_3p_a_at
ILMN_1792689
PH_hs_0028833
TC06000167.hg
U90551_at
Participates
as a member of
Ub-histone HIST1 H2A [nucleoplasm] (Homo sapiens)
Other forms of this molecule
K63polyUb-HIST1H2AC [nucleoplasm]
Ack6-HIST1H2AC [nucleoplasm]
Me2aR30-HIST1H2AC [nucleoplasm]
MeR30-HIST1H2AC [nucleoplasm]
Me2aR4-HIST1H2AC [nucleoplasm]
MeR4-HIST1H2AC [nucleoplasm]
Me2sR4-HIST1H2AC [nucleoplasm]
Me2aR12-HIST1H2AC [nucleoplasm]
MeR12-HIST1H2AC [nucleoplasm]
HIST1H2AC [extracellular region]
Ack-HIST1H2AC [nucleoplasm]
HIST1H2AC [nucleoplasm]
Inferred To
LOC100485548 [nucleoplasm]
(Xenopus tropicalis)
LOC100487632 [nucleoplasm]
(Xenopus tropicalis)
LOC116411633 [nucleoplasm]
(Xenopus tropicalis)
his-35 [nucleoplasm]
(Caenorhabditis elegans)
LOC110261482 [nucleoplasm]
(Sus scrofa)
HTA1 [nucleoplasm]
(Saccharomyces cerevisiae)
Ub-HIST3H2A [nucleoplasm]
(Gallus gallus)
Ub-HIST3H2A [nucleoplasm]
(Plasmodium falciparum)
HTA2 [nucleoplasm]
(Saccharomyces cerevisiae)
H2aj [nucleoplasm]
(Mus musculus)
H2aj [nucleoplasm]
(Rattus norvegicus)
H2Av2 [nucleoplasm]
(Dictyostelium discoideum)
Homologues of Ub-HIST3H2A [nucleoplasm]
(Caenorhabditis elegans)
Homologues of Ub-HIST3H2A [nucleoplasm]
(Danio rerio)
Homologues of Ub-HIST3H2A [nucleoplasm]
(Dictyostelium discoideum)
Homologues of Ub-HIST3H2A [nucleoplasm]
(Drosophila melanogaster)
Homologues of Ub-HIST3H2A [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of Ub-HIST3H2A [nucleoplasm]
(Schizosaccharomyces pombe)
Homologues of Ub-HIST3H2A [nucleoplasm]
(Xenopus tropicalis)
His2A:CG33862 [nucleoplasm]
(Drosophila melanogaster)
hta1 [nucleoplasm]
(Schizosaccharomyces pombe)
his-65 [nucleoplasm]
(Caenorhabditis elegans)
hta2 [nucleoplasm]
(Schizosaccharomyces pombe)
h2ac16 [nucleoplasm]
(Xenopus tropicalis)
LOC116407737 [nucleoplasm]
(Xenopus tropicalis)
LOC100487067 [nucleoplasm]
(Xenopus tropicalis)
H2AC6 [nucleoplasm]
(Bos taurus)
H2AC6 [nucleoplasm]
(Canis familiaris)
h2ax1 [nucleoplasm]
(Danio rerio)
zgc:56685 [nucleoplasm]
(Danio rerio)
H2AX [nucleoplasm]
(Dictyostelium discoideum)
H2Av3 [nucleoplasm]
(Dictyostelium discoideum)
htas-1 [nucleoplasm]
(Caenorhabditis elegans)
H2Av1 [nucleoplasm]
(Dictyostelium discoideum)
LOC101732059 [nucleoplasm]
(Xenopus tropicalis)
His2A:CG33859 [nucleoplasm]
(Drosophila melanogaster)
Modified Residues
Name
ubiquitinylated lysine (monoUb [nucleoplasm]) at 120
Coordinate
120
Modification
monoUb [nucleoplasm]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_003503.1
OpenTargets
ENSG00000180573
GeneCards
Q93077
HPA
ENSG00000180573-H2AC6
Ensembl
ENST00000377791
,
ENST00000602637
,
ENSP00000321389
,
ENST00000314088
,
ENSP00000473534
,
ENSP00000367022
,
ENSG00000180573
PRO
Q93077
Pharos - Targets
Q93077
HMDB Protein
HMDBP01936
PDB
8OX1
,
8X19
,
8OOS
,
6UPL
,
8OOP
,
7U47
,
8OO7
,
8OX0
,
6UPK
,
8X15
,
7U46
,
7A08
,
7U4D
,
6MUP
,
7YWX
,
8X1C
,
7PII
,
6C0W
,
7YYH
,
7Y8R
,
7R5R
,
6MUO
,
8OOA
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P46379-2 BAG6
0.556
3
UniProt:O14901 KLF11
0.556
3
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