RNA Pol II initiates transcription from damaged DNA template

Stable Identifier
R-HSA-6781818
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RNA Pol II initiates transcription from damaged DNA template
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Once the transcription is initiated from a DNA template that contains an RNA polymerase II (RNA Pol II) promoter, RNA Pol II synthesizes mRNA in the presence of the elongation complex TFIIH until the damaged DNA base(s) is reached (Brueckner et al. 2007).
Literature References
PubMed ID Title Journal Year
17290000 CPD damage recognition by transcribing RNA polymerase II

Brueckner, F, Hennecke, U, Carell, T, Cramer, P

Science 2007
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Authored
Gopinathrao, G  (2004-02-02)
Hoeijmakers, JH  (2004-01-29)
Orlic-Milacic, M  (2015-06-16)
Reviewed
Fousteri, M  (2015-08-03)
Created
Orlic-Milacic, M  (2015-06-02)
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