Reactome | THBS4 [extracellular region]

THBS4 [extracellular region]

Stable Identifier

R-HSA-66524

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Thrombospondin 4 precursor

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by Receptor Tyrosine Kinases (Homo sapiens)
  - Signaling by PDGF (Homo sapiens)
    - PDGF binds to extracellular matrix proteins (Homo sapiens)
      - Extracellular matrix ligands [extracellular region] (Homo sapiens)
        
        Thrombospondin [extracellular region] (Homo sapiens)
        
        THBS4 [extracellular region] (Homo sapiens)
      - PDGF A and B chains:ECM complex [extracellular region] (Homo sapiens)
        
        Extracellular matrix ligands [extracellular region] (Homo sapiens)
        
        Thrombospondin [extracellular region] (Homo sapiens)
        
        THBS4 [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:P35443 THBS4

Gene Names

THBS4, TSP4

Chain

signal peptide:1-26, chain:27-961

Reference Genes

BioGPS Gene:7060 THBS4

COSMIC (genes):THBS4 THBS4

CTD Gene:7060 THBS4

dbSNP Gene:7060 THBS4

ENSEMBL:ENSG00000113296 THBS4

ENSEMBL:ENSG00000113296.14 THBS4

HGNC:11788 THBS4

KEGG Gene (Homo sapiens):7060 THBS4

Monarch:7060 THBS4

NCBI Gene:7060 THBS4

OMIM:600715 THBS4

UCSC:P35443 THBS4

Reference Transcript

Other Identifiers

103_at

11721212_a_at

16986655

204776_PM_at

204776_at

2817585

2817586

2817587

2817588

2817593

2817594

2817596

2817598

2817599

2817601

2817602

2817603

2817605

2817606

2817607

2817608

2817609

2817611

2817612

2817614

2817615

2817616

2817620

2817621

2817622

2817623

7060

8106573

A_14_P101459

A_14_P134855

A_24_P260443

GE60362

GO:0001938

GO:0002376

GO:0005178

GO:0005509

GO:0005515

GO:0005576

GO:0005604

GO:0005615

GO:0005783

GO:0006986

GO:0007155

GO:0007165

GO:0008083

GO:0008201

GO:0016525

GO:0016529

GO:0023052

GO:0030312

GO:0031012

GO:0034103

GO:0034976

GO:0036211

GO:0043226

GO:0048018

GO:0048266

GO:0048771

GO:0048856

GO:0048870

GO:0050731

GO:0051451

GO:0051781

GO:0062023

GO:0070062

GO:0071603

GO:0090023

GO:0098772

HMNXSV003052558

ILMN_1736078

PH_hs_0025002

TC05000394.hg

Z19585_at

g4507488_3p_at

Participates

as a member of

Thrombospondin [extracellular region] (Homo sapiens)

Inferred To

Tsp [extracellular region] (Drosophila melanogaster)

THBS4 [extracellular region] (Bos taurus)

THBS4 [extracellular region] (Canis familiaris)

THBS4 [extracellular region] (Gallus gallus)

THBS4 [extracellular region] (Sus scrofa)

thbs4b [extracellular region] (Danio rerio)

Dmel\CG9297 [extracellular region] (Drosophila melanogaster)

Homologues of THBS4 [extracellular region] (Drosophila melanogaster)

Thbs4 [extracellular region] (Mus musculus)

Thbs4 [extracellular region] (Rattus norvegicus)

thbs4 [extracellular region] (Xenopus tropicalis)

Cross References

RefSeq

NP_001293141.1, NP_003239.2, NP_001293142.1, NP_001293143.1

OpenTargets

ENSG00000113296

HPA

ENSG00000113296-THBS4

GeneCards

P35443

Ensembl

ENSP00000339730, ENSG00000113296, ENST00000350881

PRO

P35443

Pharos - Targets

P35443