Reactome | THBS4 [extracellular region]

THBS4 [extracellular region]

Stable Identifier

R-HSA-66524

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Thrombospondin 4 precursor

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by Receptor Tyrosine Kinases (Homo sapiens)
  - Signaling by PDGF (Homo sapiens)
    - PDGF binds to extracellular matrix proteins (Homo sapiens)
      - Extracellular matrix ligands [extracellular region] (Homo sapiens)
        
        Thrombospondin [extracellular region] (Homo sapiens)
        
        THBS4 [extracellular region] (Homo sapiens)
      - PDGF A and B chains:ECM complex [extracellular region] (Homo sapiens)
        
        Extracellular matrix ligands [extracellular region] (Homo sapiens)
        
        Thrombospondin [extracellular region] (Homo sapiens)
        
        THBS4 [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:P35443 THBS4

Gene Names

THBS4, TSP4

Chain

signal peptide:1-26, chain:27-961

Reference Genes

BioGPS Gene:7060 THBS4

COSMIC (genes):THBS4 THBS4

CTD Gene:7060 THBS4

dbSNP Gene:7060 THBS4

ENSEMBL:ENSG00000113296 THBS4

HGNC:11788 THBS4

KEGG:hsa:7060 THBS4

Monarch:7060 THBS4

NCBI Gene:7060 THBS4

OMIM:600715 THBS4

UCSC:P35443 THBS4

Reference Transcript

Other Identifiers

103_at

11721212_a_at

16986655

204776_PM_at

204776_at

2817577

2817585

2817586

2817587

2817588

2817593

2817594

2817596

2817598

2817599

2817601

2817602

2817603

2817605

2817606

2817607

2817608

2817609

2817611

2817612

2817613

2817614

2817615

2817616

2817618

2817620

2817621

2817622

2817623

2817624

7060

8106573

A_14_P101459

A_14_P134855

A_21_P0012834

A_24_P260443

GE603587

GE60362

GO:0001938

GO:0005178

GO:0005509

GO:0005515

GO:0005576

GO:0005604

GO:0005615

GO:0005783

GO:0006986

GO:0007155

GO:0007165

GO:0008083

GO:0008201

GO:0016525

GO:0016529

GO:0030312

GO:0031012

GO:0034103

GO:0034976

GO:0043226

GO:0048018

GO:0048266

GO:0048771

GO:0048870

GO:0050731

GO:0051451

GO:0051781

GO:0062023

GO:0070062

GO:0071603

GO:0090023

GO:0098772

HMNXSV003050378

HMNXSV003052558

ILMN_1736078

PH_hs_0025002

TC05000394.hg

TC05002473.hg

Z19585_at

g4507488_3p_at

Participates

as a member of

Thrombospondin [extracellular region] (Homo sapiens)

Inferred To

Tsp [extracellular region] (Drosophila melanogaster)

THBS4 [extracellular region] (Bos taurus)

THBS4 [extracellular region] (Canis familiaris)

THBS4 [extracellular region] (Gallus gallus)

THBS4 [extracellular region] (Sus scrofa)

thbs4b [extracellular region] (Danio rerio)

Homologues of THBS4 [extracellular region] (Drosophila melanogaster)

Thbs4 [extracellular region] (Mus musculus)

Thbs4 [extracellular region] (Rattus norvegicus)

thbs4 [extracellular region] (Xenopus tropicalis)

tmn [extracellular region] (Drosophila melanogaster)

Cross References

ENSEMBL

ENSP00000339730, ENSG00000113296, ENST00000350881

OpenTargets

ENSG00000113296

GeneCards

THBS4

HPA

ENSG00000113296-THBS4

PRO

P35443

Pharos - Targets

P35443

GlyGen

P35443

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