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SLC28A2 [plasma membrane]
Stable Identifier
R-HSA-64025
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
solute carrier family 28 (sodium-coupled nucleoside transporter), member 2, Concentrative nucleoside transporter 2, CNT2, Sodium/nucleoside cotransporter 2 (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Concentrative nucleoside transporter 2) (CNT 2) (hCNT2) (Sodium/purine nucleoside co- transporter) (SPNT), Sodium/nucleoside cotransporter 2, Na(+)/nucleoside cotransporter 2, Sodium-coupled nucleoside transporter 2, CNT 2, hCNT2, Sodium/purine nucleoside co- transporter, SPNT
Locations in the PathwayBrowser
Expand all
Drug ADME (Homo sapiens)
Azathioprine ADME (Homo sapiens)
SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Homo sapiens)
SLC28A2,3 [plasma membrane] (Homo sapiens)
SLC28A2 [plasma membrane] (Homo sapiens)
Ribavirin ADME (Homo sapiens)
SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Homo sapiens)
SLC28A2,3 [plasma membrane] (Homo sapiens)
SLC28A2 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Homo sapiens)
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Homo sapiens)
SLC28A2 [plasma membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
9435697
Na+-dependent purine nucleoside transporter from human kidney: cloning and functional characterization
Giacomini, KM
,
Schaner, ME
,
Washington, CB
,
Su, SF
,
Dresser, MJ
,
Wang, J
Am J Physiol Renal Physiol
1997
External Reference Information
External Reference
UniProt:O43868 SLC28A2
Gene Names
SLC28A2, CNT2
Chain
chain:1-658
Reference Genes
BioGPS Gene:9153 SLC28A2
COSMIC (genes):SLC28A2 SLC28A2
CTD Gene:9153 SLC28A2
dbSNP Gene:9153 SLC28A2
ENSEMBL:ENSG00000137860 SLC28A2
HGNC:11002 SLC28A2
KEGG:hsa:9153 SLC28A2
Monarch:9153 SLC28A2
NCBI Gene:9153 SLC28A2
OMIM:606208 SLC28A2
UCSC:O43868 SLC28A2
Reference Transcript
RefSeq:XM_011522198.2 SLC28A2
RefSeq:NM_004212.3 SLC28A2
Other Identifiers
11737953_a_at
16800590
207249_3p_s_at
207249_PM_s_at
207249_s_at
34057_at
3592310
3592312
3592314
3592317
3592318
3592319
3592321
3592322
3592323
3592324
3592325
3592326
3592327
3592328
3592329
3592330
3592331
3592334
3592337
3592338
3592339
3592340
3592341
3592342
3592343
3592344
3592345
3592346
7983447
9153
A_14_P104013
A_23_P48816
GE62513
GO:0001895
GO:0003013
GO:0005215
GO:0005326
GO:0005337
GO:0005345
GO:0005415
GO:0005886
GO:0006139
GO:0006805
GO:0006836
GO:0006855
GO:0012506
GO:0015211
GO:0015213
GO:0015389
GO:0015855
GO:0015860
GO:0015862
GO:0016020
GO:0016327
GO:0030135
GO:0031410
GO:0031526
GO:0032238
GO:0035340
GO:0043226
GO:0045117
GO:0055085
GO:0072531
GO:0150104
GO:1901474
GO:1901642
GO:1904823
HMNXSV003039873
ILMN_1801886
PH_hs_0017522
TC15000354.hg
g4759131_3p_s_at
Participates
as a member of
SLC28A2,3 [plasma membrane] (Homo sapiens)
Inferred To
Slc28a2 [plasma membrane]
(Mus musculus)
Slc28a2 [plasma membrane]
(Rattus norvegicus)
SLC28A2 [plasma membrane]
(Bos taurus)
SLC28A2 [plasma membrane]
(Gallus gallus)
SLC28A2 [plasma membrane]
(Sus scrofa)
slc-28.1 [plasma membrane]
(Caenorhabditis elegans)
slc-28.2 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLC28A2 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLC28A2 [plasma membrane]
(Drosophila melanogaster)
CNT2 [plasma membrane]
(Drosophila melanogaster)
slc28a2 [plasma membrane]
(Xenopus tropicalis)
CNT1 [plasma membrane]
(Drosophila melanogaster)
Cross References
ZINC - World Drugs
S28A2_HUMAN
Guide to Pharmacology - Targets
1115
ENSEMBL
ENST00000347644
,
ENSP00000315006
OpenTargets
ENSG00000137860
ZINC - FDA approved
S28A2_HUMAN
ZINC - Substances
S28A2_HUMAN
ZINC - Biogenic
S28A2_HUMAN
ZINC target
O43868
PRO
O43868
ZINC - Metabolites
S28A2_HUMAN
HPA
ENSG00000137860-SLC28A2
Pharos - Targets
O43868
ZINC - Predictions - Purchasable
S28A2_HUMAN
HMDB Protein
HMDBP02043
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