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POR [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-59988
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
NADPH-cytochrome P450 reductase , CPR, P450R
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
POR reduces CYP450:Fe3+ to CYP450:Fe2+ (Homo sapiens)
POR [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P16435 POR
Gene Names
POR, CYPOR
Chain
initiator methionine:1, chain:2-677
Reference Genes
BioGPS Gene:5447 POR
COSMIC (genes):POR POR
CTD Gene:5447 POR
dbSNP Gene:5447 POR
ENSEMBL:ENSG00000127948 POR
HGNC:9208 POR
Monarch:5447 POR
NCBI Entrez Gene:5447 POR
OMIM:124015 POR
UCSC:P16435 POR
Reference Transcript
RefSeq:NM_001382657.2 POR
RefSeq:NM_001382658.3 POR
RefSeq:NM_001395413.1 POR
RefSeq:NM_001382659.3 POR
RefSeq:NM_000941.2 POR
RefSeq:NM_001367562.3 POR
Other Identifiers
11716114_x_at
11746973_x_at
11748368_x_at
11757517_x_at
17047411
208928_PM_at
208928_at
3009230
3009231
3009232
3009233
3009237
3009238
3009239
3009240
3009243
3009244
3009245
3009246
3009247
3009248
3009249
3009250
3009251
3009252
3009253
3009254
3009255
3009256
3009257
3009258
3009259
3009260
3009261
3009262
3009263
3009264
3009265
3009267
3009282
3009294
3009295
3009296
3009298
5447
8133670
858_at
A_14_P126137
A_24_P29723
A_33_P3410895
GE62990
GO:0003958
GO:0004128
GO:0005515
GO:0005737
GO:0005783
GO:0005789
GO:0005829
GO:0006091
GO:0006575
GO:0006629
GO:0006805
GO:0006809
GO:0007584
GO:0008047
GO:0008941
GO:0009055
GO:0009410
GO:0009437
GO:0009725
GO:0009812
GO:0010181
GO:0016020
GO:0016491
GO:0016787
GO:0019395
GO:0019899
GO:0022900
GO:0032332
GO:0043066
GO:0043226
GO:0043231
GO:0043602
GO:0045880
GO:0046210
GO:0047726
GO:0050660
GO:0050661
GO:0061913
GO:0070988
GO:0071371
GO:0071372
GO:0071375
GO:0071548
GO:0090031
GO:0090346
GO:0098772
HMNXSV003024604
HMNXSV003033987
HMNXSV003055259
ILMN_1677768
PH_hs_0023963
RNA95028|RNS_110_195
S90469_at
g9964002_3p_s_at
Cross References
RefSeq
NP_001369586.2
,
NP_001369587.2
,
NP_001369588.2
,
NP_001354491.2
,
NP_001382342.1
,
NP_000932.3
OpenTargets
ENSG00000127948
ENSEMBL
ENSG00000127948
,
ENST00000461988
,
ENSP00000419970
ZINC - Substances
NCPR_HUMAN
ZINC target
P16435
PRO
P16435
GlyGen
P16435
PDB
5FA6
,
3QE2
,
3QFS
,
3QFC
,
1B1C
,
5EMN
,
3QFR
,
3FJO
,
3QFT
HPA
ENSG00000127948-POR
GeneCards
POR
Pharos - Targets
P16435
Orphanet
POR
HMDB Protein
HMDBP00183
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O00264 PGRMC1
2
PGRMC1 [plasma membrane]
(R-HSA-6806314)
PGRMC1 [specific granule membrane]
(R-HSA-6799648)
0.682
6
UniProt:Q9Y5X2 SNX8
0.643
4
UniProt:P00181 CP2C2
0.576
4
UniProt:P0DTD1-PRO_0000449620 REP
0.527
2
UniProt:P54136 RARS1
1
RARS [cytosol]
(R-HSA-379586)
0.527
2
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