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SELP [plasma membrane]
Stable Identifier
R-HSA-58510
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
P-selectin precursor, Granule membrane protein 140, GMP-140, PADGEM, CD62P, Leukocyte-endothelial cell adhesion molecule 3, LECAM3
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Cell surface interactions at the vascular wall (Homo sapiens)
P-selectin binds P-selectin ligand (Homo sapiens)
Selectins [plasma membrane] (Homo sapiens)
SELP [plasma membrane] (Homo sapiens)
Selectins:2xSELPG [plasma membrane] (Homo sapiens)
Selectins [plasma membrane] (Homo sapiens)
SELP [plasma membrane] (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Surface deployment of platelet alpha granule membrane components (Homo sapiens)
Platelet alpha granule membrane components that are released on degranulation [plasma membrane] (Homo sapiens)
SELP [plasma membrane] (Homo sapiens)
Surface deployment of platelet dense granule membrane components (Homo sapiens)
Platelet dense granule membrane components [plasma membrane] (Homo sapiens)
SELP [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P16109 SELP
Gene Names
SELP, GMRP, GRMP
Chain
signal peptide:1-41, chain:42-830
Reference Genes
BioGPS Gene:6403 SELP
COSMIC (genes):SELP SELP
CTD Gene:6403 SELP
dbSNP Gene:6403 SELP
ENSEMBL:ENSG00000174175 SELP
HGNC:10721 SELP
KEGG:hsa:6403 SELP
Monarch:6403 SELP
NCBI Gene:6403 SELP
OMIM:173610 SELP
UCSC:P16109 SELP
Reference Transcript
RefSeq:XM_005245435.1 SELP
RefSeq:NM_003005.3 SELP
RefSeq:XM_005245436.3 SELP
Other Identifiers
11755826_a_at
16696217
206049_PM_at
206049_at
2443418
2443419
2443420
2443422
2443423
2443424
2443425
2443426
2443427
2443428
2443430
2443431
2443432
2443433
2443436
2443437
2443438
2443439
2443440
2443441
2443442
2443445
2443446
2443448
2443449
40366_at
6403
7922200
A_23_P137697
A_33_P3339100
GE58293
GO:0001530
GO:0002376
GO:0002687
GO:0005178
GO:0005509
GO:0005515
GO:0005615
GO:0005886
GO:0006954
GO:0007155
GO:0007157
GO:0007159
GO:0008201
GO:0008289
GO:0009897
GO:0010572
GO:0012505
GO:0016020
GO:0016339
GO:0030246
GO:0031088
GO:0031092
GO:0032496
GO:0033623
GO:0033691
GO:0034097
GO:0042806
GO:0043208
GO:0046872
GO:0048306
GO:0048870
GO:0050829
GO:0050900
GO:0050901
GO:0051897
GO:0070492
GO:0098542
GO:0098609
GO:1903238
HMNXSV003020369
HMNXSV003024175
ILMN_1715417
M25322_at
PH_hs_0004216
TC01003499.hg
g6031196_3p_at
Participates
as a member of
Platelet dense granule membrane components [plasma membrane] (Homo sapiens)
Platelet alpha granule membrane components that are released on degranulation [plasma membrane] (Homo sapiens)
Selectins [plasma membrane] (Homo sapiens)
Other forms of this molecule
SELP [platelet dense granule membrane]
SELP [platelet alpha granule membrane]
Inferred To
SELP [plasma membrane]
(Bos taurus)
SELP [plasma membrane]
(Canis familiaris)
SELP [plasma membrane]
(Gallus gallus)
SELP [plasma membrane]
(Mus musculus)
SELP [plasma membrane]
(Rattus norvegicus)
SELP [plasma membrane]
(Sus scrofa)
selp [plasma membrane]
(Danio rerio)
cfh-1 [plasma membrane]
(Caenorhabditis elegans)
hig [plasma membrane]
(Drosophila melanogaster)
Cross References
Guide to Pharmacology - Targets
3103
ENSEMBL
ENSP00000263686
,
ENST00000263686
OpenTargets
ENSG00000174175
HPA
ENSG00000174175-SELP
ZINC - Substances
LYAM3_HUMAN
ZINC - Biogenic
LYAM3_HUMAN
ZINC target
P16109
PRO
P16109
Pharos - Targets
P16109
ZINC - Predictions - Purchasable
LYAM3_HUMAN
HMDB Protein
HMDBP02132
PDB
1G1S
,
1G1Q
,
1FSB
,
1G1R
,
1HES
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14242 SELPLG
1
SELPLG [plasma membrane]
(R-HSA-202777)
0.722
4
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