Reactome | ASXL2 [nucleoplasm]

ASXL2 [nucleoplasm]

Stable Identifier

R-HSA-5689629

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Putative Polycomb group protein ASXL2, ASXL2_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Deubiquitination (Homo sapiens)
    - UCH proteinases (Homo sapiens)
      - BAP1 binds BAP1-interacting complex (Homo sapiens)
        
        BAP1-interacting complex [nucleoplasm] (Homo sapiens)
        
        BAP1-interacting core complex [nucleoplasm] (Homo sapiens)
        
        ASXL1,ASXL2 [nucleoplasm] (Homo sapiens)
        
        ASXL2 [nucleoplasm] (Homo sapiens)
        
        BAP1:BAP1-interacting complex [nucleoplasm] (Homo sapiens)
        
        BAP1-interacting complex [nucleoplasm] (Homo sapiens)
        
        BAP1-interacting core complex [nucleoplasm] (Homo sapiens)
        
        ASXL1,ASXL2 [nucleoplasm] (Homo sapiens)
        
        ASXL2 [nucleoplasm] (Homo sapiens)
      - Histone H2A is dubiquitinated by the PR-DUB complex (Homo sapiens)
        
        PR-DUB complex [nucleoplasm] (Homo sapiens)
        
        PR-DUB core complex [nucleoplasm] (Homo sapiens)
        
        ASXL1,ASXL2 [nucleoplasm] (Homo sapiens)
        
        ASXL2 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q76L83 ASXL2

Gene Names

ASXL2, ASXH2, KIAA1685

Chain

chain:1-1435

Reference Genes

BioGPS Gene:55252 ASXL2

COSMIC (genes):ASXL2 ASXL2

CTD Gene:55252 ASXL2

dbSNP Gene:55252 ASXL2

ENSEMBL:ENSG00000143970 ASXL2

HGNC:23805 ASXL2

Monarch:55252 ASXL2

NCBI Gene:55252 ASXL2

OMIM:612991 ASXL2

UCSC:Q76L83 ASXL2

Reference Transcript

RefSeq:NM_018263.4 ASXL2

Other Identifiers

11726047_a_at

11726048_x_at

11751891_a_at

11757756_s_at

11758949_at

1555266_PM_a_at

1555266_a_at

16895431

16895434

218659_PM_at

218659_at

226251_PM_at

226251_at

229359_PM_at

229359_at

237095_PM_at

237095_at

240072_PM_at

240072_at

2544918

2544920

2544922

2544923

2544924

2544926

2544927

2544928

2544929

2544930

2544931

2544932

2544933

2544934

2544935

2544936

2544937

2544938

2544939

2544940

2544941

2544942

2544944

2544945

2544946

2544947

2544949

2544953

2544954

2544955

2544956

2544957

2544958

2544959

2544964

2544967

2544968

2544978

2544990

2544991

55252

63317_at

78465_at

8050875

81340_at

83541_at

83628_at

A_21_P0002653

A_23_P210300

A_24_P359771

A_33_P3248610

GE673905

GE794685

GE82331

GO:0003677

GO:0003682

GO:0005515

GO:0005634

GO:0005654

GO:0006355

GO:0009887

GO:0035360

GO:0035517

GO:0042975

GO:0043226

GO:0045600

GO:0045944

GO:0046872

HMNXSV003010043

HMNXSV003037379

Hs.102946.0.A1_3p_at

Hs.118977.0.A1_3p_at

Hs.156304.0.A1_3p_at

Hs.190064.0.A1_3p_at

Hs2.13801.2.S1_3p_s_at

ILMN_1698968

ILMN_1910893

PH_hs_0035495

TC02001663.hg

TC02004121.hg

g8922749_3p_at

p20794

Participates

as a member of

ASXL1,ASXL2 [nucleoplasm] (Homo sapiens)

Inferred To

Asxl2 [nucleoplasm] (Mus musculus)

Asxl2 [nucleoplasm] (Rattus norvegicus)

ASXL2 [nucleoplasm] (Bos taurus)

ASXL2 [nucleoplasm] (Canis familiaris)

ASXL2 [nucleoplasm] (Gallus gallus)

ASXL2 [nucleoplasm] (Sus scrofa)

Asx [nucleoplasm] (Drosophila melanogaster)

asxl2 [nucleoplasm] (Xenopus tropicalis)

Cross References

ENSEMBL

ENST00000404843, ENST00000435504, ENSP00000391447, ENSP00000383920

OpenTargets

ENSG00000143970

HPA

ENSG00000143970-ASXL2

PRO

Q76L83

Pharos - Targets

Q76L83

GlyGen

Q76L83

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92560 BAP1	1	BAP1 [nucleoplasm] (R-HSA-5689665)	0.643	5