Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
TRAF7 [cytosol]
Stable Identifier
R-HSA-5688973
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase TRAF7 ecNumber6.3.2.-/ecNumber, TRAF7_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6Q0C0 TRAF7
Gene Names
TRAF7, RFWD1, RNF119
Chain
chain:1-670
Reference Genes
BioGPS Gene:84231 TRAF7
COSMIC (genes):TRAF7 TRAF7
CTD Gene:84231 TRAF7
dbSNP Gene:84231 TRAF7
ENSEMBL:ENSG00000131653.13 TRAF7
HGNC:20456 TRAF7
KEGG Gene (Homo sapiens):84231 TRAF7
Monarch:84231 TRAF7
NCBI Gene:84231 TRAF7
OMIM:606692 TRAF7
UCSC:Q6Q0C0 TRAF7
Reference Transcript
RefSeq:NM_032271.2 TRAF7
Other Identifiers
0000730170
11743349_a_at
11754528_s_at
16815001
223029_PM_s_at
223029_s_at
223031_PM_s_at
223031_s_at
3644540
3644545
3644546
3644547
3644548
3644549
3644554
3644555
3644556
3644557
3644558
3644559
3644561
3644562
3644564
3644566
3644571
3644574
3644576
3644578
3644580
3644582
3644584
3644585
3644586
3644587
3644588
3644589
3644590
45250_at
45251_g_at
65739_at
7992529
84231
A_14_P118746
A_23_P206474
A_24_P53150
GE83356
GO:0000027
GO:0000151
GO:0004842
GO:0005515
GO:0005622
GO:0005634
GO:0005730
GO:0005737
GO:0005886
GO:0006915
GO:0007219
GO:0008270
GO:0012501
GO:0016567
GO:0016740
GO:0023052
GO:0031410
GO:0032991
GO:0036211
GO:0042254
GO:0043226
GO:0043231
GO:0043410
GO:0046872
GO:0065003
GO:0070372
GO:0140096
GO:2001235
HMNXSV003047740
Hs.181077.0.S1_3p_a_at
ILMN_1654408
ILMN_2405991
PH_hs_0023801
TC16000063.hg
g12053336_3p_a_at
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
Homologues of TRAF7 [cytosol]
(Plasmodium falciparum)
TRAF7 [cytosol]
(Caenorhabditis elegans)
TRAF7 [cytosol]
(Plasmodium falciparum)
TRAF7 [cytosol]
(Sus scrofa)
rsa4 [cytosol]
(Schizosaccharomyces pombe)
Traf7 [cytosol]
(Mus musculus)
Traf7 [cytosol]
(Rattus norvegicus)
Nle [cytosol]
(Drosophila melanogaster)
traf7 [cytosol]
(Xenopus tropicalis)
RSA4 [cytosol]
(Saccharomyces cerevisiae)
nle1 [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_115647.2
OpenTargets
ENSG00000131653
GeneCards
Q6Q0C0
HPA
ENSG00000131653-TRAF7
Ensembl
ENSP00000318944
,
ENSG00000131653
,
ENST00000326181
PRO
Q6Q0C0
Pharos - Targets
Q6Q0C0
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text