pro-SFTPC translocates from ER membrane to multivesicle body

Stable Identifier
R-HSA-5684868
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
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Surfactant proteins (SFTPs) are trafficked from the ER membrane to lamellar bodies (LBs) via the multi-vesicle body (MVB). The pro-SFTPs B and C are cleaved here to produce functional SFTPs (Conkright et al. 2001).

Literature References
PubMed ID Title Journal Year
11278984 Secretion of surfactant protein C, an integral membrane protein, requires the N-terminal propeptide

Conkright, JJ, Bridges, JP, Na, CL, Voorhout, WF, Trapnell, B, Glasser, SW, Weaver, TE

J. Biol. Chem. 2001
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