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SFTPB dimer,C translocate from multivesicle body to lamellar body
Stable Identifier
R-HSA-5684865
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
multivesicular body lumen
,
lamellar body
ReviewStatus
5/5
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Metabolism of proteins (Homo sapiens)
Surfactant metabolism (Homo sapiens)
SFTPB dimer,C translocate from multivesicle body to lamellar body (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The mature surfactant proteins B dimer and C (SFTPB dimer and C) are translocated to lamellar bodies (LBs), ready for secretion (Whitsett et al. 2010). The mechanism of transport is unknown.
Literature References
PubMed ID
Title
Journal
Year
19824815
Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease
Whitsett, JA
,
Weaver, TE
,
Wert, SE
Annu. Rev. Med.
2010
Participants
Input
SFTPB dimer [multivesicular body lumen]
(Homo sapiens)
SFTPC(24-58) [multivesicular body lumen]
(Homo sapiens)
Output
SFTPB dimer [lamellar body]
(Homo sapiens)
SFTPC [lamellar body]
(Homo sapiens)
Participates
as an event of
Surfactant metabolism (Homo sapiens)
Orthologous Events
SFTPB dimer,C translocate from multivesicle body to lamellar body (Bos taurus)
SFTPB dimer,C translocate from multivesicle body to lamellar body (Canis familiaris)
SFTPB dimer,C translocate from multivesicle body to lamellar body (Gallus gallus)
SFTPB dimer,C translocate from multivesicle body to lamellar body (Mus musculus)
SFTPB dimer,C translocate from multivesicle body to lamellar body (Rattus norvegicus)
SFTPB dimer,C translocate from multivesicle body to lamellar body (Sus scrofa)
Authored
Jassal, B (2015-03-23)
Reviewed
D'Eustachio, P (2015-08-17)
Created
Jassal, B (2015-03-23)
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