Methionine is oxidised to methionine sulfoxide

Stable Identifier
R-HSA-5676912
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Methionine is oxidised to methionine sulfoxide
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Methionine can be oxidised by naturally-occurring reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) to form methionine sulfoxide (MetO), and by further oxidation to a methyl sulfone derivative (MetOO). Oxidation of methionine results in a mixture of the diastereomers methionine-(S)-S-oxide and methionine-(R)-S-oxide (Lavine 1947, Kim et al. 2014).

Literature References
Participants
Input
Output
Participant Of
hasEvent
Authored
Jupe, S  (2015-01-05)
Reviewed
Meldal, BH  (2015-10-05)
Created
Jupe, S  (2015-02-20)
Cite Us!