Methionine is oxidised to methionine sulfoxide

Stable Identifier
R-HSA-5676912
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
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Methionine is oxidised to methionine sulfoxide
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Methionine can be oxidised by naturally-occurring reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) to form methionine sulfoxide (MetO), and by further oxidation to a methyl sulfone derivative (MetOO). Oxidation of methionine results in a mixture of the diastereomers methionine-(S)-S-oxide and methionine-(R)-S-oxide (Lavine 1947, Kim et al. 2014).

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Authored
Jupe, S  (2015-01-05)
Reviewed
Meldal, BH  (2015-10-05)
Created
Jupe, S  (2015-02-20)
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