PAK1 phosphorylates FLNA

Stable Identifier
R-HSA-5669250
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Activated PAK1 phosphorylates FLNA (filamin A) on serine residue S2152 in vitro and in vivo. FLNA is involved in PAK1-induced formation of membrane ruffles (Vadlamudi et al. 2002).

Literature References
PubMed ID Title Journal Year
12198493 Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1

Vadlamudi, RK, Li, F, Adam, L, Nguyen, D, Ohta, Y, Stossel, TP, Kumar, R

Nat. Cell Biol. 2002
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of p-S144,T423-PAK1:FLNA [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Created