SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin

Stable Identifier
R-HSA-5665802
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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SRGAP2 binds FMNL1 activated by RAC1:GTP by simultaneously interacting with RAC1 and FMNL1. SRGAP2 co-localizes with RAC1, FMNL1, profilin and actin at the plasma membrane after RAC1-mediated activation of FMNL1 (Mason et al. 2011).

Literature References
PubMed ID Title Journal Year
21148482 Bi-modal regulation of a formin by srGAP2

Mason, FM, Heimsath, EG, Higgs, HN, Soderling, SH

J. Biol. Chem. 2011
Participants
Participant Of
Orthologous Events
Authored
Created