TP63/TP53 bind the DDIT4 gene promoter

Stable Identifier
R-HSA-5632393
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

DDIT4 (REDD1) gene has a p53 response element immediately upstream of the transcription start site, and this p53 response element is able to bind both TP63 and TP53 transcription factors (Ellisen et al. 2002).

Literature References
PubMed ID Title Journal Year
12453409 REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species

Ellisen, LW, Ramsayer, KD, Johannessen, CM, Yang, A, Beppu, H, Minda, K, Oliner, JD, McKeon, F, Haber, DA

Mol. Cell 2002
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