TP63/TP53 bind the DDIT4 gene promoter

Stable Identifier
R-HSA-5632393
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
TP63/TP53 bind the DDIT4 gene promoter
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
DDIT4 (REDD1) gene has a p53 response element immediately upstream of the transcription start site, and this p53 response element is able to bind both TP63 and TP53 transcription factors (Ellisen et al. 2002).
Literature References
PubMed ID Title Journal Year
12453409 REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species

Ellisen, LW, Ramsayer, KD, Johannessen, CM, Yang, A, Beppu, H, Minda, K, Oliner, JD, McKeon, F, Haber, DA

Mol. Cell 2002
Participants
Input
Output
Participates
as an event of
Authored
Orlic-Milacic, M  (2014-12-23)
Reviewed
Hwang, PM  (2014-12-30)
Kang, JG  (2014-12-30)
Wang, PY  (2014-12-30)
Inga, A  (2016-02-04)
Zaccara, S  (2016-02-04)
Created
Orlic-Milacic, M  (2014-10-28)
Cite Us!