p-T774-PKN1:AR:Androgen complex translocates to the nucleus

Stable Identifier
R-HSA-5625738
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
ReviewStatus
5/5
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p-T774-PKN1:AR:Androgen complex translocates to the nucleus
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Binding of activated PKN1 to the androgen-activated AR (androgen receptor) promotes translocation of the p-T774-PKN1:AR:Androgen complex into the nucleus (Metzger et al. 2003).

Literature References
PubMed ID Title Journal Year
12514133 A novel inducible transactivation domain in the androgen receptor: implications for PRK in prostate cancer

Schüle, R, Metzger, E, Müller, JM, Ferrari, S, Buettner, R

EMBO J. 2003
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Orthologous Events
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Bos taurus)
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Canis familiaris)
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Danio rerio)
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Drosophila melanogaster)
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Mus musculus)
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Rattus norvegicus)
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Sus scrofa)
Authored
Orlic-Milacic, M  (2014-10-24)
Rivero Crespo, F  (2014-12-26)
Created
Orlic-Milacic, M  (2014-10-07)
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