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SLC22A12 [plasma membrane]
Stable Identifier
R-HSA-561098
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
URAT1, Urate transporter 1, Solute carrier family 22 member 12, S22AC_HUMAN
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Organic cation/anion/zwitterion transport (Homo sapiens)
Organic anion transport (Homo sapiens)
SLC22A12 exchanges extracellular urate for cytosolic LACT (Homo sapiens)
SLC22A12 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96S37 SLC22A12
Gene Names
SLC22A12, OATL4, URAT1, UNQ6453/PRO34004
Chain
chain:1-553
Reference Genes
BioGPS Gene:116085 SLC22A12
COSMIC (genes):SLC22A12 SLC22A12
CTD Gene:116085 SLC22A12
dbSNP Gene:116085 SLC22A12
ENSEMBL:ENSG00000197891 SLC22A12
HGNC:17989 SLC22A12
KEGG:hsa:116085 SLC22A12
Monarch:116085 SLC22A12
NCBI Gene:116085 SLC22A12
OMIM:607096 SLC22A12
UCSC:Q96S37 SLC22A12
Reference Transcript
RefSeq:NM_001276326.1 SLC22A12
RefSeq:NM_001276327.1 SLC22A12
RefSeq:NM_153378.2 SLC22A12
RefSeq:NM_144585.3 SLC22A12
Other Identifiers
116085
11728625_a_at
16726549
237799_PM_at
237799_at
3334660
3334661
3334662
3334663
3334665
3334666
3334668
3334669
3334670
3334671
3334672
3334673
3334674
3334675
3334676
3334677
3334679
7941074
84833_at
A_14_P120448
A_23_P35809
A_33_P3316721
GE79878
GE860245
GO:0003014
GO:0005215
GO:0005886
GO:0006811
GO:0009410
GO:0015143
GO:0015711
GO:0015747
GO:0016020
GO:0016324
GO:0019725
GO:0022857
GO:0030165
GO:0031526
GO:0032869
GO:0043226
GO:0046415
GO:0055085
GO:0070062
GO:0097744
HMNXSV003003970
HMNXSV003015593
HMNXSV003017553
Hs.174424.0.A1_3p_at
ILMN_1662154
ILMN_1766083
ILMN_2408748
PH_hs_0010446
TC11000606.hg
Other forms of this molecule
SLC22A12 L418R [plasma membrane]
SLC22A12 G361V [plasma membrane]
SLC22A12 R90H [plasma membrane]
SLC22A12 E298D [plasma membrane]
SLC22A12 W258* [plasma membrane]
Inferred To
Orct [plasma membrane]
(Drosophila melanogaster)
Dmel\CG16727 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG14855 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4630 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG7342 [plasma membrane]
(Drosophila melanogaster)
pes-23 [plasma membrane]
(Caenorhabditis elegans)
Dmel\CG10486 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG6356 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG5592 [plasma membrane]
(Drosophila melanogaster)
CG6596 [plasma membrane]
(Drosophila melanogaster)
CT19169 [plasma membrane]
(Drosophila melanogaster)
CarT [plasma membrane]
(Drosophila melanogaster)
oct-2 [plasma membrane]
(Caenorhabditis elegans)
suex-2 [plasma membrane]
(Caenorhabditis elegans)
CG31530-RA [plasma membrane]
(Drosophila melanogaster)
CG8654-RA [plasma membrane]
(Drosophila melanogaster)
Dmel\CG17752 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG7333 [plasma membrane]
(Drosophila melanogaster)
Orct2 [plasma membrane]
(Drosophila melanogaster)
Homologues of SLC22A12 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLC22A12 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4465 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG14857 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4462 [plasma membrane]
(Drosophila melanogaster)
oct-1 [plasma membrane]
(Caenorhabditis elegans)
Dmel\CG7084 [plasma membrane]
(Drosophila melanogaster)
Balat [plasma membrane]
(Drosophila melanogaster)
Dmel\CG14856 [plasma membrane]
(Drosophila melanogaster)
SLC22A12 [plasma membrane]
(Bos taurus)
SLC22A12 [plasma membrane]
(Caenorhabditis elegans)
SLC22A12 [plasma membrane]
(Canis familiaris)
SLC22A12 [plasma membrane]
(Sus scrofa)
Dmel\CG6231 [plasma membrane]
(Drosophila melanogaster)
SLC22A [plasma membrane]
(Drosophila melanogaster)
Dmel\CG17751 [plasma membrane]
(Drosophila melanogaster)
Slc22a12 [plasma membrane]
(Mus musculus)
Slc22a12 [plasma membrane]
(Rattus norvegicus)
Dmel\CG7458 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG4459 [plasma membrane]
(Drosophila melanogaster)
Cross References
Guide to Pharmacology - Targets
1031
OpenTargets
ENSG00000197891
ENSEMBL
ENSP00000366797
,
ENSP00000366795
,
ENSP00000438437
,
ENST00000336464
,
ENST00000377567
,
ENST00000473690
,
ENSG00000197891
,
ENST00000377572
,
ENSP00000336836
,
ENST00000377574
,
ENSP00000366790
ZINC - Substances
S22AC_HUMAN
ZINC - Biogenic
S22AC_HUMAN
ZINC target
Q96S37
PRO
Q96S37
GlyGen
Q96S37
PDB
8WJQ
,
9JDV
,
9B1K
,
9B1I
,
9B1J
,
9B1H
,
9B1G
,
9B1F
,
8WJG
,
9B1N
,
9B1L
,
9JDZ
,
9B1O
,
9B1M
ZINC - Metabolites
S22AC_HUMAN
HPA
ENSG00000197891-SLC22A12
GeneCards
SLC22A12
Pharos - Targets
Q96S37
Orphanet
SLC22A12
ZINC - Predictions - Purchasable
S22AC_HUMAN
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