TRAF6 oligomerizes

Stable Identifier
R-HSA-5607751
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
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TRAF6 oligomerizes
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The MALT1 oligomers bound to TRAF6 induce TRAF6 oligomerization and activate TRAF6 E3 ubiquitin ligase activity (Sun et al. 2004).

Literature References
PubMed ID Title Journal Year
15125833 The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

Sun, L, Deng, L, Ea, CK, Xia, ZP, Chen, ZJ

Mol Cell 2004
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Authored
Garapati, P V  (2014-07-14)
Reviewed
Geijtenbeek, TB  (2014-09-02)
Created
Garapati, P V  (2014-07-14)