BCL10 binds CARD9

Stable Identifier
R-HSA-5607733
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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B-cell lymphoma/leukemia 10 (BCL10) is the downstream signaling partner of CARD9 and it interacts selectively with the CARD activation domain of CARD9. BCL10 functions as an adaptor between the effector IKK complex and the proximal signaling complexes that interact with CARD9 (Bertin et al. 2000).

Literature References
PubMed ID Title Journal Year
11053425 CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B

Bertin, J, Guo, Y, Wang, L, Srinivasula, SM, Jacobson, MD, Poyet, JL, Merriam, S, Du, MQ, Dyer, MJ, Robison, KE, DiStefano, PS, Alnemri, ES

J. Biol. Chem. 2000
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created