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p-S176,S180-IKKA dimer [cytosol]
Stable Identifier
R-HSA-5607702
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
TNFR2 non-canonical NF-kB pathway (Homo sapiens)
NIK-->noncanonical NF-kB signaling (Homo sapiens)
Active NIK phosphorylates IKKA dimer (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer:p100:RELB [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB (Homo sapiens)
Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP (Homo sapiens)
Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
p100:RELB binds active NIK:p-IKKA dimer (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer:p100:RELB [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
Innate Immune System (Homo sapiens)
C-type lectin receptors (CLRs) (Homo sapiens)
CLEC7A (Dectin-1) signaling (Homo sapiens)
Dectin-1 mediated noncanonical NF-kB signaling (Homo sapiens)
Active NIK phosphorylates IKKA dimer (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer:p100:RELB [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB (Homo sapiens)
Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP (Homo sapiens)
Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
p100:RELB binds active NIK:p-IKKA dimer (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer:p100:RELB [cytosol] (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
p-S176,S180-IKKA dimer [cytosol] (Homo sapiens)
Participants
components
x 2
p-S176,S180-CHUK [cytosol]
(Homo sapiens)
Participates
as a component of
Active NIK:p-S176,180-IKKA dimer [cytosol] (Homo sapiens)
Inferred To
p-S176,S180-IKKA dimer [cytosol]
(Bos taurus)
p-S176,S180-IKKA dimer [cytosol]
(Canis familiaris)
p-S176,S180-IKKA dimer [cytosol]
(Drosophila melanogaster)
p-S176,S180-IKKA dimer [cytosol]
(Gallus gallus)
p-S176,S180-IKKA dimer [cytosol]
(Mus musculus)
p-S176,S180-IKKA dimer [cytosol]
(Rattus norvegicus)
p-S176,S180-IKKA dimer [cytosol]
(Sus scrofa)
p-S176,S180-IKKA dimer [cytosol]
(Xenopus tropicalis)
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