Reactome | CACNA2D1(25-956) [plasma membrane]

CACNA2D1(25-956) [plasma membrane]

Stable Identifier

R-HSA-5577182

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Voltage-dependent calcium channel subunit alpha 2-1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P54289 CACNA2D1

Gene Names

CACNA2D1, CACNL2A, CCHL2A, MHS3

Chain

signal peptide:1-24, chain:25-1103, chain:25-956, chain:957-1103

Reference Genes

BioGPS Gene:781 CACNA2D1

COSMIC - genes:CACNA2D1 CACNA2D1

CTD Gene:781 CACNA2D1

dbSNP Gene:781 CACNA2D1

ENSEMBL:ENSG00000153956 CACNA2D1

HGNC:1399 CACNA2D1

KEGG:hsa:781 CACNA2D1

Monarch:781 CACNA2D1

NCBI Gene:781 CACNA2D1

OMIM:114204 CACNA2D1

UCSC:P54289 CACNA2D1

Reference Transcript

Other Identifiers

11751259_a_at

17059195

207050_PM_at

207050_at

227623_PM_at

227623_at

3059006

3059007

3059008

3059011

3059013

3059014

3059015

3059016

3059017

3059018

3059019

3059020

3059021

3059022

3059024

3059025

3059026

3059027

3059028

3059029

3059030

3059031

3059033

3059034

3059036

3059038

3059039

3059040

3059041

3059042

3059043

3059044

3059045

3059048

3059049

3059052

3059053

3059054

3059059

3059063

3059064

3059067

3059071

3059075

3059080

3059120

3059127

3059147

3059148

3059149

3059150

3059151

35527_at

65904_at

74099_at

781

8140579

A_23_P82379

A_33_P3232478

GE574347

GE620213

GO:0005245

GO:0005262

GO:0005886

GO:0005891

GO:0006811

GO:0006816

GO:0016020

GO:0016529

GO:0030315

GO:0034220

GO:0034702

GO:0046872

GO:0048787

GO:0051924

GO:0055085

GO:0060307

GO:0060402

GO:0061577

GO:0070062

GO:0070588

GO:0086002

GO:0086007

GO:0086048

GO:0086057

GO:0086091

GO:0098703

GO:0098903

GO:0098982

GO:0098992

GO:1902514

GO:1904646

GO:1990454

HMNXSV003012929

HMNXSV003029551

Hs.298258.0.A1_3p_at

ILMN_1768533

M76559_at

PH_hs_0031836

TC07001563.hg

TC07003044.hg

g4757893_3p_at

p26398

Participates

as a component of

CACNA2D1a:CACNA2D1d [plasma membrane] (Homo sapiens)

Other forms of this molecule

CACNA2D1(957-1103) [plasma membrane]

Modified Residues

Name

Inter-chain Crosslink via L-cystine (cross-link) at 404 and 1059

Coordinate

404

PsiMod Name

L-cystine (cross-link)

PsiMod Definition

A protein modification that effectively cross-links two L-cysteine residues to form L-cystine.

Cross References

RefSeq

XP_005250631.1, NP_001353796.1, XP_005250629.1, NP_000713.2, XP_054214955.1, XP_005250630.1, XP_054214950.1, XP_054214953.1

ZINC - World Drugs

CA2D1_HUMAN

OpenTargets

ENSG00000153956

ENSEMBL

ENSG00000153956, ENSP00000409374, ENST00000443883, ENSP00000349320, ENST00000356860

ZINC - FDA approved

CA2D1_HUMAN

ZINC - Substances

CA2D1_HUMAN

ZINC target

P54289

PRO

P54289

PDB

8IF4, 8IF3, 7YG5, 8E59, 7XLQ, 8HMA, 8WEA, 8WE7, 8WE9, 8EPM, 8EPL, 8WE8, 8HMB, 8WE6, 7MIX, 7MIY, 8X91, 8X90, 8X93, 8FHS, 8E5A, 8E5B, 7VFW, 8HLP, 7VFV, 7VFS, 7VFU, 7UHF, 7UHG

HPA

ENSG00000153956-CACNA2D1

GeneCards

CACNA2D1

Pharos - Targets

P54289

Orphanet

CACNA2D1

ZINC - Predictions - Purchasable

CA2D1_HUMAN

HMDB Protein

HMDBP07484