Phase 2 - plateau phase

Stable Identifier
R-HSA-5576893
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Phase 2 - plateau phase
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Phase 2 of the cardiac action potential is the plateau phase which is sustained by a balance of Ca2+ influx through L-type Ca2+ channels (LTCCs) and K+ efflux through the slow delayed rectifier K+ channel 1 (KCNQ1). This phase sustains muscle contraction (Park & Fishman 2011, Grant 2009).
Literature References
PubMed ID Title Journal Year
21357845 The cardiac conduction system

Park, DS, Fishman, GI

Circulation 2011
19808464 Cardiac ion channels

Grant, AO

Circ Arrhythm Electrophysiol 2009
Participants
Events
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Event Information
Go Biological Process
cardiac conduction (0061337)
Orthologous Events
Phase 2 - plateau phase (Bos taurus)
Phase 2 - plateau phase (Caenorhabditis elegans)
Phase 2 - plateau phase (Canis familiaris)
Phase 2 - plateau phase (Drosophila melanogaster)
Phase 2 - plateau phase (Gallus gallus)
Phase 2 - plateau phase (Mus musculus)
Phase 2 - plateau phase (Rattus norvegicus)
Phase 2 - plateau phase (Sus scrofa)
Phase 2 - plateau phase (Xenopus tropicalis)
Authored
Jassal, B  (2014-05-27)
Reviewed
Colotti, G  (2015-11-09)
Created
Jassal, B  (2014-05-27)
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